Whole Brain Emulation Achieved: Scientists Run a Fruit Fly Brain in Simulation
bloody hell this is amazing. As Charlie Stross noted:
They've mapped the neural connectome of Drosophila and simulated it in silico. The experimenters went on to hook up their Drosophila connectome to an anatomically detailed Drosophila body model within an open-source physics engine that "uses generalized coordinates and constraint-based contact dynamics to simulate rigid-body systems with high fidelity" including joint and antennae modeling and accurate modeling of surface adhesion—and compound eye simulation.
They managed to run a feedback loop between the full 127,400 neuron network in the biological connectome to the physical simulation, with feedback from proprioceptive signals received by the model "fly" in the simulation producing feedback spile trains in the simulation, and THEY GOT RESULTS:
The behavioral repertoire observed in the demonstration included coordinated hexapod locomotion with both tripod and metachronal walking gaits, spontaneous postural correction in response to perturbation, initiation and execution of full antennal grooming sequences with the tripartite synchronization described by Özdil et al., and natural transitions between walking and stationary states. Every behavior arose from the same running brain model - there was no switching between different neural circuits or controllers. This is precisely what happens in a living fly: walking, grooming, and balance are different motor programs that coexist in the same brain and are selected and executed by the same biological circuits depending on the moment-to-moment state of the animal and its environment.
Absolutely mind blowing -- a reconstructed, biological brain running in silico.
Tags: simulation brains uploading drosophila flies emulation science biology neurons