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this is incredible — the word roughly translates as “improvised fixes”, “hacks” or “McGyverism”, that kind of thing. fantastic Image Search
(tags: images gambiarra fixes thereifixedit mcgyver hacks kludges funny brazil)
Cillian De Gascun on Twitter: “A short thread on PCR #SARSCoV2”
Decent thread on Irish RT-PCR COVID-19 testing. tl;dr: Ct levels are not reliable in our system, and cannot be used to quantify viral load reliably
(tags: ireland covid-19 testing ct-levels viral-load viruses cillian-de-gascun twitter)
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Keith Dawson summarises a recent discussion on TWiV regarding COVID-19, the current batch of vaccines under development, and sterilising vs. protective immunity. it’s not great news
(tags: immunity immune-system twiv covid-19 alan-dove vaccines)
Category: Uncategorized
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report from Benchspace on their open source PPE project during March and April. it’s great stuff. 50,000 face shields printed!
(tags: face-shields covid-19 volunteers open-source 3d-printing ppe benchspace)
America Is Trapped in a Pandemic Spiral – The Atlantic
‘Many Americans trusted intuition to help guide them through this disaster. They grabbed onto whatever solution was most prominent in the moment, and bounced from one (often false) hope to the next. They saw the actions that individual people were taking, and blamed and shamed their neighbors. They lapsed into magical thinking, and believed that the world would return to normal within months. Following these impulses was simpler than navigating a web of solutions, staring down broken systems, and accepting that the pandemic would rage for at least a year. These conceptual errors were not egregious lies or conspiracy theories, but they were still dangerous. They manifested again and again, distorting the debate around whether to stay at home, wear masks, or open colleges. They prevented citizens from grasping the scope of the crisis and pushed leaders toward bad policies. And instead of overriding misleading intuitions with calm and considered communication, those leaders intensified them. The country is now trapped in an intuition nightmare: Like the spiraling ants, Americans are walled in by their own unhelpful instincts, which lead them round and round in self-destructive circles.’
FactFind: No, it’s not correct to say just 100 people have died from Covid-19 in Ireland
The Journal’s fact checking team are knocking it out of the park once again — great debunking of Ben Gilroy’s latest viral claims regarding “pre-existing conditions” and COVID-19
(tags: covid-19 medicine ben-gilroy conspiracies qanon the-journal fact-checking debunking)
QAnon is a Nazi Cult, Rebranded
A secret cabal is taking over the world. They kidnap children, slaughter, and eat them to gain power from their blood. They control high positions in government, banks, international finance, the news media, and the church. They want to disarm the police. They promote homosexuality and pedophilia. They plan to mongrelize the white race so it will lose its essential power. Does this conspiracy theory sound familiar? It is. The same narrative has been repackaged by QAnon. […] The plot, described above, was the conspiracy “revealed” in the most influential anti-Jewish pamphlet of all time. It was called The Protocols of the Elders of Zion. It was written by Russian anti-Jewish propagandists around 1902.
(tags: qanon politics conspiracy-theories history nazism nazis antisemitism)
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via Vincent Glad, on Twitter: the positivity rate stratified by age, in the Marseilles region
(tags: testing covid-19 age epidemiology dataviz statistics marseilles france)
The timing of COVID-19 transmission
new preprint on medRxiv:
We examined the distribution of transmission events with respect to exposure and onset of symptoms. We show that for symptomatic individuals, the timing of transmission of SARS-CoV-2 is more strongly linked to the onset of clinical symptoms of COVID-19 than to the time since infection. We found that it was approximately centered and symmetric around the onset of symptoms, with three quarters of events occurring in the window from 2-3 days before to 2-3 days after. However, we caution against overinterpretation of the right tail of the distribution, due to its dependence on behavioural factors and interventions. We also found that the pre-symptomatic infectious period extended further back in time for individuals with longer incubation periods. This strongly suggests that information about when a case was infected should be collected where possible, in order to assess how far into the past their contacts should be traced. Overall, the fraction of transmission from strictly pre-symptomatic infections was high (41%; 95%CI 31-50%), which limits the efficacy of symptom-based interventions, and the large fraction of transmissions (35%; 95%CI 26-45%) that occur on the same day or the day after onset of symptoms underlines the critical importance of individuals distancing themselves from others as soon as they notice any symptoms, even if they are mild. Rapid or at-home testing and contextual risk information would greatly facilitate efficient early isolation.
(tags: covid-19 transmission infection epidemiology)
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the latest hot new image format — pretty impressive compression numbers vs quality thresholds here
[MA] Post-it notes left in apartment. : legaladvice
Classic Reddit thread. Guy finds mysterious post-it notes around his apartment, suspects his landlord is breaking in and leaving them. I won’t spoil it, but it’s quite a twist ending…
(tags: reddit stories legaladvice apartments landlords post-its)
Starbucks Cafe’s Covid Outbreak Spared Employees Who Wore Masks – Bloomberg
This was pretty striking: ‘A person sitting under an air conditioner infected 27 others with coronavirus at a Starbucks cafe in South Korea, but none of the employees, who were wearing masks, got the virus.’ Another great case writeup from South Korea (Via Andrew Flood)
(tags: via:andrewflood covid-19 korea ventilation air-conditioning aircon masks transmission)
_COVID-19: Interim Public Health guidance for the management of COVID-19 outbreaks_ [pdf]
The current guidance doc for outbreak management in Ireland
Proactive screening for COVID-19 is individually costly
Thread from Professor Carl T. Bergstrom:
[…] proactive testing carries individual costs: those associated with purchasing the tests, time costs of taking them, and serious social and economic costs if one tests positive and has to self-isolate for upward of a week. So, we have an intervention that is costly to you but beneficial to others. We need to think about what the incentives are for people to (1) decide to take a daily test before the results are known and (2) follow through appropriately if a test comes up positive.
(tags: testing covid-19 screening costs economics incentives)
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A complete guide via the Native Woodland Trust for planting trees in your garden, hedge, etc.
Good thread on the current state of play re COVID-19 in Ireland and the rest of Europe
Ewan Birney on Twitter: “Like I suspect a number of scientists I’ve been quizzed by a variety of friends and family on COVID, and its gone up recently because (a) school is back and so people can feel change around them and (b) there is a change in stats in across countries in Europe.”
Darmok and Jalad at Tanagra, in memes
large number of people in a theatre, applauding
(tags: memes gifs reaction-gifs funny darmok-and-jalad sttng star-trek)
Keith Dawson on This Week in Virology
a paean to my favourite podcast
Death, sex, superstition and fear: the hawthorn tree in Ireland
These trees that grew of their own accord, unplanted by human hands, are those most regarded with fear and superstition. These are thought of as faery trees, associated with those unseen beings from the other world. They are believed to mark the places where the faeries, after dark, would assemble and play sweet ethereal music, ready to abduct any beautiful human who took their fancy. Faeries could potentially destroy the crops, livestock, health, fortune or luck of anyone they took a dislike to, or anyone who had somehow wronged them. Thus, anything associated with faery activity in Ireland was traditionally avoided by the people who used many rituals to appease them.
(tags: hawthorn trees superstition fairies sidhe history ireland folklore)
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via DrZoeHyde: ‘Important pre-print study (interpret cautiously) of 992 UK children showing 6.9% had #SARSCoV2 antibodies, suggesting they are at similar risk of infection as adults, & that young and older children are similarly susceptible. 50% were asymptomatic.’ ‘Half of the children (50%) who had antibodies against #SARSCoV2 were asymptomatic (although this may be subject to recall bias). The most common symptoms were fever (31%), gastrointestinal symptoms such as diarrhoea and vomiting (19%), and headache (18%). Only 38% of children who tested positive had fever, cough, or changes in smell or taste. Therefore, the majority of children did not meet criteria for #COVID19 testing in the UK. Current testing strategies [in the UK] will fail to diagnose most cases in children.’
(tags: covid-19 symptoms kids schools sars-cov-2 studies preprints papers uk testing)
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‘This is one of the most horrifying stories I’ve ever read about policing: Because of a flawed algorithm, cops showed up 21 TIMES in 5 months to a 15 year-olds house. He was not accused of any crime.’
(tags: civil-rights police algorithms policing automation florida us-politics)
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One person on a bus infected 23 others, probably through the air during a 100-minute trip. A/C was on with recirculation. Infected people were randomly scattered throughout the bus, not just near the index case.
(tags: covid-19 aerosols airborne transmission diseases buses public-transport travel sars-cov-2)
Gerät 32620: the machine that powered numerous number stations
Fascinating details of the hardware behind “number stations”, the mysterious radio stations broadcasting streams of numbers in a monotone. One example of their use is the story of Gabriele Gast: ‘After agreeing to help [the Stasi], Gast very soon found herself sent on an intensive spycraft course, including hands-on training with the latest in covert communications equipment. She was given a Stasi code name, “Gisela”, which came with a false passport and a new handbag, incorporating a well concealed secret compartment. Back home in Aachen, every Tuesday evening at the same time she tuned into a shortwave radio station from East Germany and carefully wrote down a long line of numbers, read out in a monotone, without further elaboration, by a “radio presenter”. When she decrypted the messages from Schmidt she found some were instructions while others were simply encouraging love messages.’
(tags: spies number-stations 1980s history ussr hardware encryption gabriele-gast germany)
FAQs on Protecting Yourself from Aerosol Transmission of COVID-19
This is pretty extensive
(tags: faqs covid-19 aerosols transmission)
Keeping CALM: When Distributed Consistency Is Easy | September 2020 | Communications of the ACM
‘Consistency As Logical Monotonicity (CALM): A problem has a consistent, coordination-free distributed implementation if and only if it is monotonic.’
(tags: calm computer-science consistency distributed-systems bloom distcomp)
Two metres or one: what is the evidence for physical distancing in covid-19? | The BMJ
Key messages: Current rules on safe physical distancing are based on outdated science Distribution of viral particles is affected by numerous factors, including air flow Evidence suggests SARS-CoV-2 may travel more than 2 m through activities such as coughing and shouting Rules on distancing should reflect the multiple factors that affect risk, including ventilation, occupancy, and exposure time
(tags: epidemiology coronavirus covid-19 papers bmj social-distancing physical-distancing 2-metres aerosols)
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TIL about credit card “interchange fees” — an additional fee levied by credit card companies and banks, roughly 3%, mainly in the US (the EU regulations cap it at 0.3%). ‘Imagine a consumer making a $100 purchase with a credit card. For that $100 item, the retailer would get approximately $98. The remaining $2, known as the merchant discount[13] and fees, gets divided up.’
(tags: fees credit-cards interchange-fees us money)
How I helped fix Canada?s COVID Alert app
Nice writeup of using mitmproxy to detect unwanted accesses to a Google endpoint in an iOS app
interesting results on children and COVID-19 — high asymptomatic infection rate
‘METHODS: We conducted a prospective cohort study of children and adolescents (<21 years of age) with a SARS-CoV-2-infected close contact. We collected nasopharyngeal or nasal swabs at enrollment and tested for SARS-CoV-2 using a real-time PCR assay. RESULTS: Of 382 children, 293 (77%) were SARS-CoV-2-infected. SARS-CoV-2-infected children were more likely to be Hispanic (p<0.0001), less likely to have asthma (p=0.005), and more likely to have an infected sibling contact (p=0.001) than uninfected children. Children ages 6-13 years were frequently asymptomatic (39%) and had respiratory symptoms less often than younger children (29% vs. 48%; p=0.01) or adolescents (29% vs. 60%; p<0.0001). Compared to children ages 6-13 years, adolescents more frequently reported influenza-like (61% vs. 39%; p<0.0001), gastrointestinal (27% vs. 9%; p=0.002), and sensory symptoms (42% vs. 9%; p<0.0001), and had more prolonged illnesses [median (IQR) duration: 7 (4, 12) vs. 4 (3, 8) days; p=0.01]. Despite the age-related variability in symptoms, we found no differences in nasopharyngeal viral load by age or between symptomatic and asymptomatic children.’
Children in close contact with a confirmed case of Covid-19 were not contacted for nine days
‘Children who came into close contact with a confirmed case of the coronavirus at a summer camp run by Ireland’s lead sporting authority were not contacted by the HSE regarding the issue for nine days, it has emerged. Sport Ireland, the State authority charged with the development of sport in Ireland, has been running childrens’ summer camps at the National Aquatic Centre campus in Blanchardstown, Dublin, where SI itself is headquartered, since June 29th. At one such camp on Friday, 14 August, a nine-year-old boy participating apparently came into close contact with a case of the virus. However, he heard nothing about the contact until nine days later on August 23 when his mother received an automated text message stating that the contact had occurred and that he had been referred for a Covid-19 test.’
(tags: sport-ireland ireland contact-tracing covid-19 kids hse children)
Irish coins designed by Percy Metcalfe
the coins used in Ireland between 1928 and 2000 (when the Euro became standard here). Beautiful, classic designs
Asymptomatic SARS-CoV-2 infections: a living systematic review and meta-analysis | medRxiv
‘The overall estimate of the proportion of people who become infected with SARS-CoV-2 and remain asymptomatic throughout infection was 20% (95% CI 17-25) with a prediction interval of 3-67% in 79 studies that addressed this review question.’ — note, asymptomatic throughout infection, not including presymptomatic then symptomatic. (via Andrew Flood)
(tags: via:andrewflood covid-19 asymptomatic papers preprints medicine)
Explanation of the “cases rising but deaths staying static” COVID-19 phenomenon
Featuring lots of graphs and data. This is great
Long-Haulers Are Redefining COVID-19 – The Atlantic
god, this disease is awful
(tags: long-haulers covid-19 health medicine ed-yong)
Richard Neher on Twitter: “What happens to #COVID19 when winter returns”
tl;dr: ‘this suggests controlling #SARSCoV2 in the Northern Hemisphere will become a lot harder over the next six months and things might spiral out of control quickly.’
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The incubation period distribution may be modelled with a lognormal distribution with pooled mu and sigma parameters (95% CIs) of 1.63 (95% CI 1.51 to 1.75) and 0.50 (95% CI 0.46 to 0.55), respectively. The corresponding mean (95% CIs) was 5.8 (95% CI 5.0 to 6.7) days. It should be noted that uncertainty increases towards the tail of the distribution: the pooled parameter estimates (95% CIs) resulted in a median incubation period of 5.1 (95% CI 4.5 to 5.8) days, whereas the 95th percentile was 11.7 (95% CI 9.7 to 14.2) days.
(tags: covid-19 incubation diseases sars-cov-2 papers bmj)
How to Test Every American for COVID-19, Every Day – The Atlantic
Good write-up on Dr. Michael Mina’s testing plan, using quick, cheap testing strips for daily COVID-19 testing
(tags: testing covid-19 coronavirus michael-mina reopening)
A-Levels: The Model is not the Student
Solid description of the many errors in the UK’s attempt to estimate correct grades for their A-level students this year. They really made a massive mess of it. ‘Ultimately, the government can only receive, at best, a D for their efforts; they tried but failed. We can only hope they will now pull themselves up, bring in the experts, and construct an algorithm worthy of an A.’
(tags: ofqual schools marks exams a-levels uk estimation statistics maths fail)
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“The story behind one of the most infamous myths of the Irish pandemic.” Great analysis by The Journal here.
(tags: covid-19 paddy-cosgrave twitter misinformation tweets)
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“Over the next 50 years, keeping to the 2°C pathway would prevent roughly 4.5 million premature deaths, about 3.5 million hospitalizations and emergency room visits, and approximately 300 million lost workdays in the US.” All that prevented death, illness, and lost productivity adds up to a lot of savings: The avoided deaths are valued at more than $37 trillion. The avoided health care spending due to reduced hospitalizations and emergency room visits exceeds $37 billion, and the increased labor productivity is valued at more than $75 billion. On average, this amounts to over $700 billion per year in benefits to the US from improved health and labor alone, far more than the cost of the energy transition. Importantly, many of the benefits can be accessed in the near term. Right now, air pollution leads to almost 250,000 premature deaths a year in the US. Within a decade, aggressive decarbonization could reduce that toll by 40 percent; over 20 years, it could save around 1.4 million American lives that would otherwise be lost to air quality. Of the potential yearly deaths prevented, Rep. Robin Kelly of Illinois remarked at the hearing, “That’s a huge number. That’s nearly three times the number of lives we lose in car accidents every year. It’s twice the number of deaths caused by opioids in the past few years. And it’s even more than the number of Americans we lose to diabetes each year.”
(tags: pollution air energy environment climate-change air-quality health decarbonization)
ESB PVC Ducting Pipe Red 50mm x 6M
decent weatherproof ducting for running cables to garden sheds etc.
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Some prime quotes: ‘You can’t infer the correct grades at an individual level from the prior year’s distribution of grades, no matter how hard you clonk away at the abacus.’ ‘The data *doesn’t* allow that. ThIs puts idea that grade inflation, school level results and maintaining the distribution shape is more important than the fairness of individual results.’ ‘I don’t blame Ofqual, but they’re being asked to correctly estimate the size of each egg that went into an omelette, based on a different omelette.’
(tags: ofqual uk education covid-19 estimation a-levels grades schools)
Robust T cell immunity in convalescent individuals with asymptomatic or mild COVID-19: Cell
Good news for ongoing immunity:
SARS-CoV-2-specific memory T cells will likely prove critical for long-term immune protection against COVID-19. We here systematically mapped the functional and phenotypic landscape of SARS-CoV-2-specific T cell responses in unexposed individuals, exposed family members, and individuals with acute or convalescent COVID-19. Acute phase SARS-CoV-2-specific T cells displayed a highly activated cytotoxic phenotype that correlated with various clinical markers of disease severity, whereas convalescent phase SARS-CoV-2-specific T cells were polyfunctional and displayed a stem-like memory phenotype. Importantly, SARS-CoV-2-specific T cells were detectable in antibody-seronegative exposed family members and convalescent individuals with a history of asymptomatic and mild COVID-19. Our collective dataset shows that SARS-CoV-2 elicits robust, broad and highly functional memory T cell responses, suggesting that natural exposure or infection may prevent recurrent episodes of severe COVID-19.
(tags: immunity covid-19 sars-cov-2 diseases immune-system t-cells)
How to use ventilation and air filtration to prevent the spread of coronavirus indoors
Given that COVID-19 spreads via aerosols in closed rooms like classrooms, use a CO2 monitor to check levels of ventilation; open windows; or use an air purifier.
(tags: covid-19 aerosols air air-quality co2 air-purifiers schools)
Covid 19 coronavirus: Freight investigated as possible source of community transmission – NZ Herald
Interesting theory in NZ — their current outbreak may have been caused by surface transmission on food shipped from China:
Surfaces in a coolstore workplace are being tested to see whether international freight may have been the origin of the new cases. One of the people who has tested positive for Covid-19 is an employee at an Americold coolstore in Mt Wellington, one of four people who tested positive on Tuesday.
(tags: shipping fomites surfaces transmission covid-19 new-zealand)
Objectives for COVID-19 testing in school settings
‘New ECDC guidance on testing for COVID-19 in schools says anyone who is in a “closed environment, such as a classroom, for more than 15 minutes” with a confirmed case is considered a close contact and should be tested’
(tags: ecdc covid-19 infection transmission airborne aerosols schools kids)
Yes, kids can get COVID-19 – 3 pediatricians explain what’s known about coronavirus and children
So: kids catch the virus at the same rate, and transmit at the same rate as adults. They just don’t tend to become symptomatic as much as adults do.
(tags: covid-19 disease kids schools transmission)
the German meat-factory COVID-19 outbreak was airborne
This is a great article:
The outbreak has been studied comprehensively by scientists using genetic sequencing techniques. The index case, who was masked, spread the disease to co-workers in a radius of more than eight metres over three days of work shifts, they found. Transmission was aided by the confined area of the plant, where air was constantly recirculated and cooled to 10 degrees. Shared apartments, bedrooms or carpools did not play a major role in the initial outbreak.
(Via Dee Gilhawley)(tags: covid-19 airborne aerosols transmission meat)
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New preprint, modelling COVID-19 transmission in Bay Area schools.
Large-scale school closures have been implemented worldwide to curb the spread of COVID-19. However, the impact of school closures and re-opening on epidemic dynamics remains unclear. Methods: We simulated COVID-19 transmission dynamics using an individual-based stochastic model, incorporating social-contact data of school-aged children during shelter-in-place orders derived from Bay Area (California) household surveys. We simulated transmission under observed conditions and counterfactual intervention scenarios between March 17-June 1, and evaluated various fall 2020 K-12 reopening strategies. Findings: Between March 17-June 1, assuming children <10 were half as susceptible to infection as older children and adults, we estimated school closures averted a similar number of infections (13,842 cases; 95% CI: 6,290, 23,040) as workplace closures (15,813; 95% CI: 9,963, 22,617) and social distancing measures (7,030; 95% CI: 3,118, 11,676). School closure effects were driven by high school and middle school closures. Under assumptions of moderate community transmission, we estimate that fall 2020 school reopenings will increase symptomatic illness among high school teachers (an additional 40.7% expected to experience symptomatic infection, 95% CI: 1.9, 61.1), middle school teachers (37.2%, 95% CI: 4.6, 58.1), and elementary school teachers (4.1%, 95% CI: -1.7, 12.0). Results are highly dependent on uncertain parameters, notably the relative susceptibility and infectiousness of children, and extent of community transmission amid re-opening. The school-based interventions needed to reduce the risk to fewer than an additional 1% of teachers infected varies by grade level. A hybrid-learning approach with halved class sizes of 10 students may be needed in high schools, while maintaining small cohorts of 20 students may be needed for elementary schools. Interpretation: Multiple in-school intervention strategies and community transmission reductions, beyond the extent achieved to date, will be necessary to avoid undue excess risk associated with school reopening. Policymakers must urgently enact policies that curb community transmission and implement within-school control measures to simultaneously address the tandem health crises posed by COVID-19 and adverse child health and development consequences of long-term school closures.
Building dashboards for operational visibility | Amazon Builders’ Library
Fantastic set of tips for metric dashboard construction, from John O’Shea
(tags: dashboards aws monitoring metrics alerts amazon)
Nisreen A Alwan: What exactly is mild covid-19?
What is now becoming clear is that mortality is not the only adverse outcome of this infection and our surveillance systems must keep up and reflect that. I am advocating for precise case definitions for covid-19 morbidity that reflect the degree of severity of infection and allow us to measure moderate and long term health and wellbeing outcomes. At this stage of the pandemic, it is vital that we accurately measure and count all degrees of infection, not only in research cohorts, but as part of population-based routine surveillance systems. This includes people like me who were not tested at the time of their initial infection. Death is not the only thing to count in this pandemic, we must count lives changed. We still know very little about covid-19, but we do know that we cannot fight what we do not measure.
Georgia camp outbreak shows rapid virus spread among children
Between 44% and 75% of the people at this summer camp were infected. ‘258 staff gathered for three days before the camp started with no precautions. Then on day 1 of camp someone [felt] chills. By day 6, the camp was closed.’ 597 attendees, 344 tested, 260 positive.
(tags: covid-19 symptoms summer-camps pandemic disease georgia kids schools children)
“Three new important studies came out in the past week about kids & COVID-19”
Good twitter thread from Megan Ranney MD: * ‘South Korea study — Older kids most likely transmit #COVID19 to their household at rates similar to adults. And younger kids transmit the virus, too. But: no masks or distancing, since this took place at home.’ * ‘Chicago — the level of the virus in kids is AT LEAST as high as the level of virus in adults. (Caveat: we don’t know whether this virus is infectious. But this data matches what we know about other respiratory viruses. The next step will be studying test swabs to see if kids’ virus can reproduce. I suspect it can. […] We can’t let kids ignore #SocialDistancing & #MaskUp just bc they’re kids.)’ * ‘States with early closure of schools had reduced levels of #COVID19 compared with states with late closure, *even after* adjusting for policies like “stay-at-home”. […] Once #COVID19 infection rates start to rise, it would be foolhardy to keep schools open IRL. And we should be planning NOW for how to keep kids healthy, safe, & fed, because that moment will likely come for every state.’ ‘Realistically, we MUST control levels of community transmission of #COVID19 if we want kids & teachers in schools. We may be able to send kids back, but we need PPE & regular, random testing of kids & teachers, whether in elementary, middle, high school, or college.’
(tags: parenting kids schools covid-19 transmission pandemics viruses sars-cov-2)
The UX of LEGO Interface Panels – George Cave
love it
RCP8.5 tracks cumulative CO2 emissions | PNAS
Today in “we are still fucked” news:
RCP8.5, the most aggressive scenario in assumed fossil fuel use for global climate models, will continue to serve as a useful tool for quantifying physical climate risk, especially over near- to midterm policy-relevant time horizons. Not only are the emissions consistent with RCP8.5 in close agreement with historical total cumulative CO2 emissions (within 1%), but RCP8.5 is also the best match out to midcentury under current and stated policies with still highly plausible levels of CO2 emissions in 2100.
RCP8.5 is the model associated with a planet where a good chunk of the globe is rendered uninhabitable.(tags: rcp8.5 grim-meathook-future future climate-change co2 pnas papers models climate)
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While the antibody response to SARS-CoV-2 has been extensively studied in blood, relatively little is known about the mucosal immune response and its relationship to systemic antibody levels. Since SARS-CoV-2 initially replicates in the upper airway, the antibody response in the oral cavity is likely an important parameter that influences the course of infection. We developed enzyme linked immunosorbent assays to detect IgA and IgG antibodies to the SARS-CoV-2 spike protein (full length trimer) and its receptor binding domain (RBD) in serum (n=496) and saliva (n=90) of acute and convalescent patients with laboratory-diagnosed COVID-19 ranging from 3-115 days post-symptom onset (PSO), compared to negative controls. Anti-CoV-2 antibody responses were readily detected in serum and saliva, with peak IgG levels attained by 16-30 days PSO. Whereas anti-CoV-2 IgA antibodies rapidly decayed, IgG antibodies remained relatively stable up to 115 days PSO in both biofluids. Importantly, IgG responses in saliva and serum were correlated, suggesting that antibodies in the saliva may serve as a surrogate measure of systemic immunity.
That last line, in particular, is good news.(tags: covid-19 immunity disease assays antibodies sars-cov-2 papers preprints)
Harvard-UC Boulder Portable Air Cleaner Calculator for Schools
A handy calculator spreadsheet to estimate how big of a portable air cleaner would be required to protect kids/teachers/admin staff at a typical US school, based on room size, ceiling height, etc. More info: https://twitter.com/cedenolaurent/status/1290447833959747584 (Catherine Lalanne notes: “Airflows in this sheet are about half the Irish regulations, American regulations are pretty weak.”)
(tags: air-cleaners filtration spreadsheets covid-19 schools kids air-quality air)
Why Aren’t We Talking More About Ventilation? – The Atlantic
Zeynep wins again:
It seems baffling that despite mounting evidence of its importance, we are stuck practicing hygiene theater — constantly deep cleaning everything — while not noticing the air we breathe. How is it that six months into a respiratory pandemic, we still have so little guidance about this all-important variable, the very air we breathe?
(tags: hygiene-theatre deep-cleaning covid-19 aerosols infection air viruses transmission zeynep-tufekci)
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‘also called Detroit agate, it’s created when layers of automotive paint build up and harden. then it’s cut and polished like other rocks.’
(tags: fordite rock agate history paint recycling cars detroit)
Apple tells app devs to use IPv6 as it’s 1.4 times faster than IPv4
“when IPv6 is in use, the median connection setup is 1.4 times faster than IPv4. This is primarily due to reduced NAT usage and improved routing.”
This is counterintuitive?(tags: ipv6 ipv4 networking apple internet performance)
Aerosol and surface contamination of SARS-CoV-2 observed in quarantine and isolation care
A paper in Nature, no less. SARS-CoV-2 is airborne and spreads via aerosols. My pal Cassie’s colleague, Travis Longcore, writes: ‘A team at the University of Nebraska collected surface and air samples from the hospital where 13 Covid-19 cases were isolated. They found evidence of virus everywhere — high-volume air samples, low-volume personal samples worn by study personnel, room surfaces, personal items, and toilets. The results are in gene copes (from SARS-CoV-2) per microL for surfaces and per L of air for airborne. Others can do the calculations, but the personal air samples had the highest numbers, and exposure would depend on mask wearing (N95 in a hospital) and the amount of throughput (liters of air in and out of the body). What you really don’t want to be doing is exercising (=high volume of air in and out) without a mask indoors with someone who is infected. Or touching anything around them. Or being inside with recirculated, unfiltered air with anyone who is infected (even if they don’t know it).’
(tags: aerosols nature papers covid-19 sars-cov-2 fomites contamination transmission infection air airborne)
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In aggregate, the distributions of Cts for viral probes used in the qRT-PCR assay were very similar, with a statistically but not meaningfully different mean (?Ct 0.71 cycles, p = 0.006) and a similar range (12-38 cycles), between populations with and without symptoms over the entire time period, across all sub-categories examined (age, race, ethnicity, sex, resident/staff).
Viral load is comparable between COVID-19 victims who are asymptomatic and symptomatic.(tags: covid-19 preprints papers medicine viral-load rt-pcr testing)
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Although SARS-CoV-2 RNA shedding in respiratory and stool can be prolonged, duration of viable virus is relatively short-lived. Thus, detection of viral RNA cannot be used to infer infectiousness. High SARS-CoV-2 titres are detectable in the first week of illness with an early peak observed at symptom onset to day 5 of illness.
…also backs up that infectiousness starts around 2 days prior to symptom onset. -
Arrow combines the benefits of columnar data structures with in-memory computing. It provides the performance benefits of these modern techniques while also providing the flexibility of complex data and dynamic schemas. And it does all of this in an open source and standardized way.
(via Tony Finch)(tags: via:fanf arrow data formats compression columnar-storage storage libraries)
Solving the expiring Root CA certificate-mageddon; partly at least | APNIC Blog
Ugh — PKI expiry lifetimes were such an awful idea.
As of writing, a large number of Samsung Blu-Ray players around the world are stuck in a reboot loop. Although customers are still waiting for the official word on the issue, the suspicion is that the problem is caused by an expired certificate that stops the device firmware from booting properly, possibly because of strict digital rights management requirements that require verification and signing before full start-up of the players. As Scott points out, there are hundreds of ageing Root CAs out there, many more when you include the intermediates. Over the next few years, more will expire.
(via Tony Finch)(tags: security fail pki ssl tls samsung firmware certificates expiration cas)
US Spring school closures tied to drastic decrease in Covid-19 cases, deaths in model
Their projection found that, if schools had stayed open, there could have been roughly 424 more coronavirus infections and 13 more deaths per 100,000 residents over the course of 26 days. Extrapolate that to the American population, and the country might have seen as many as 1.37 million more cases and 40,600 more deaths, explained Samir Shah, the director of hospital medicine at Cincinnati Children’s Hospital Medical Center and one of the authors of the paper. “These numbers seem ridiculously high and it’s mind-boggling to think that these numbers are only … in the first several weeks,” said Shah. “That’s bonkers.” He warned, though, that those numbers should be taken with a grain of salt. While their statistical model attempts to pinpoint the impact of schools staying open or being closed, the method can’t actually establish any sort of causal relationship.
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When Science looked at reopening strategies from South Africa to Finland to Israel, some encouraging patterns emerged. Together, they suggest a combination of keeping student groups small and requiring masks and some social distancing helps keep schools and communities safe, and that younger children rarely spread the virus to one another or bring it home. But opening safely, experts agree, isn’t just about the adjustments a school makes. It’s also about how much virus is circulating in the community, which affects the likelihood that students and staff will bring COVID-19 into their classrooms.
AWS User Data is Being Stored, Used Outside User’s Chosen Regions
Wow, this is staggeringly inappropriate usage. Bad move, Amazon!
[AWS] is using customers’ “AI content” for its own product development purposes. It also reserves the right in its small print to store this material outside the geographic regions that AWS customers have explicitly selected. It may also share this with AWS “affiliates” it says, without naming them.
(tags: via:corey-quinn aws amazon machine-learning corpora training data data-privacy data-protection)
The Scourge of Hygiene Theater – The Atlantic
On the pointless “deep clean”:
To some American companies and Florida men, COVID-19 is apparently a war that will be won through antimicrobial blasting, to ensure that pathogens are banished from every square inch of America’s surface area. But what if this is all just a huge waste of time? In May, the Centers for Disease Control and Prevention updated its guidelines to clarify that while COVID-19 spreads easily among speakers and sneezers in close encounters, touching a surface “isn’t thought to be the main way the virus spreads.” Other scientists have reached a more forceful conclusion. “Surface transmission of COVID-19 is not justified at all by the science,” Emanuel Goldman, a microbiology professor at Rutgers New Jersey Medical School, told me. He also emphasized the primacy of airborne person-to-person transmission.
(tags: covid-19 air aerosols transmission cleaning surfaces fomites hygiene)
Sputum testing provides higher rate of COVID-19 detection | EurekAlert! Science News
Li and his colleagues scoured the literature — both preprints and published papers — for studies that assessed at least two respiratory sampling sites using an NP swab, oropharyngeal swab or sputum. From more than 1,000 studies, they identified 11 that met their criteria. These studies included results from a total of 3,442 respiratory tract specimens. The team examined how often each collection method produced a positive result. For NP swabs, the rate was 54 percent; for oropharyngeal swabs, 43 percent; for sputum, 71 percent. The rate of viral detection was significantly higher in sputum than either oropharyngeal swabs or NP swabs. Detection rates were highest within one week of symptom onset for all three tests.
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Scent dog identification of samples from COVID-19 patients – a pilot study, in BMC Infectious Diseases:
The dogs were able to discriminate between samples of infected (positive) and non-infected (negative) individuals with average diagnostic sensitivity of 82.63% (95% confidence interval [CI]: 82.02–83.24%) and specificity of 96.35% (95% CI: 96.31–96.39%). During the presentation of 1012 randomised samples, the dogs achieved an overall average detection rate of 94% (±3.4%) with 157 correct indications of positive, 792 correct rejections of negative, 33 incorrect indications of negative or incorrect rejections of 30 positive sample presentations.
(tags: dogs good-dog covid-19 detection testing smell scent)
Top Scientists Just Ruled Out Best-Case Global Warming Scenarios – Bloomberg
“A group of 25 leading scientists now conclude that catastrophic warming is almost inevitable if emissions continue at their current rate.”
(tags: global-warming climate-change future climate science)
20 Questions to Ask before Sending your Kids Back to School – Schools For Health
An excellent checklist.
There is no such thing as “zero risk” in anything we do, and certainly not during a pandemic. There will be some risk to students, teachers, staff, and families. As such, it is important to reduce these risks to the extent possible. Returning to school should not be “school as usual.” We prepared the following set of questions as a guide for parents, teachers and school staff who may not be sure what to ask or look for at their school. While we offer some insight into the responses you might receive, and expect, each school’s response will be different because there is no “one size fits all” plan for COVID-19.
Schools Will Eventually Need to Reopen – Schools For Health
We recognize there are immense challenges. There is no perfect plan to reopen schools safely, only “less bad” options. There is no “one size fits all” strategy that works for every school. Schools have limited budgets and staff. Compliance will be imperfect. Learning will be different. There will be disruption. Schools may need to re-close unexpectedly depending on local conditions. No one knows with certainty what the fall will bring in terms of this pandemic. Despite these challenges, the enormous individual and societal costs of keeping schools closed compels us, a team focused on Healthy Buildings and exposure and risk science, to present a range of control strategies that should be considered in discussions of school reopenings.
(tags: health schools reopening covid-19 teaching kids children)
Facebook Employee Leaks Show Betrayal By Company Leadership
Wang opted for a clip of himself speaking directly to the camera. What followed was a 24-minute clear-eyed hammering of Facebook’s leadership and decision-making over the previous year. The video was a distillation of months of internal strife, protest, and departures that followed the company’s decision to leave untouched a post from President Donald Trump that seemingly called for violence against people protesting the police killing of George Floyd. And while Wang’s message wasn’t necessarily unique, his assessment of the company’s ongoing failure to protect its users — an evaluation informed by his lengthy tenure at the company — provided one of the most stunningly pointed rebukes of Facebook to date. “We are failing,” he said, criticizing Facebook’s leaders for catering to political concerns at the expense of real-world harm. “And what’s worse, we have enshrined that failure in our policies.”
Persistent Symptoms in Patients After Acute COVID-19 | Critical Care Medicine | JAMA | JAMA Network
‘This study found that in patients who had recovered from COVID-19, 87.4% reported persistence of at least 1 symptom, particularly fatigue and dyspnea.’ Two months after ‘recovery’! (via Megan Ranney MD, https://twitter.com/meganranney/status/1285354398265282563)
(tags: covid-19 recovery medicine fatigue health via:meganranney)
Cheap, Frequent, Quick Testing
Keith Dawson:
Picture the widespread availability of a simple, cheap, at-home Covid test that produces quick results. Perhaps a strip of paper like a pregnancy test. Everyone in the country takes it daily. It would stop this virus in its tracks.
An excellent summary of the Michael Mina, et al, paper (and TWiV discussion).What It Will Take to Reopen Schools Safely | American Scientist
If we want school to reopen safely in this school year, here’s what it will take: community outbreak control, extensive changes to school operations to limit infection risk (and the money to support such changes), flexibility, and transparency — in that order.
amazing long twitter thread on school reopening
‘Sarah Cohodes on Twitter: “Ok, so no one asked me (well @mathteacherjedi sort of did) what I thought the best plan for reopening schools was. And I haven’t said anything about this, because it’s not my direct area of expertise. 1/”‘
(tags: education children kids covid-19 reopening schools teaching)
Cancel Culture and the Problem of Woke Capitalism – The Atlantic
‘How Capitalism Drives Cancel Culture: Beware splashy corporate gestures when they leave existing power structures intact.’
(tags: cancel-culture cancelling capitalism society)
The inside story of how the UK government failed to develop a contact-tracing app
A classic Tory fuckup. Spoofing, over-promising, a behind-the-scenes desire to collect a database of citizen’s private medical info, and hubris.
(tags: nhsx palantir bluetooth covid-19 uk tories data-privacy nhs)
Ireland donates its contact tracing app to the Linux Foundation
This is awesome. Congrats to NearForm and the HSE for making some great choices here:
Ireland’s Health Service Executive (HSE) announced today that it is donating the code for the COVID Tracker app as Open Source to the not-for-profit Linux Foundation. This will enable jurisdictions worldwide to quickly build and deploy their own contact tracing apps using a wildly successful proven base. The donated app has been named COVID Green. […] The rapid adoption of the COVID Tracker app in Ireland exceeded all expectations. One million people installed it in the first 36 hours, and the app currently has over 1.3 million installations. That figure represents more than 30% of people in Ireland with compatible devices. The code is also being used in the app for Gibraltar and the upcoming apps for Northern Ireland, other jurisdictions in EMEA and multiple US states. NearForm continues to enable public health authorities to get a contact tracing application into production within four weeks of project start. By donating the source code to the new Linux Foundation Public Health (LFPH) project, under the Apache License 2.0, the HSE is playing an active role in helping to fight Covid-19 worldwide. Source code for the COVID Green mobile app is available now on GitHub and soon will be followed by all matching backend code. The Linux Foundation is dedicated to building sustainable ecosystems around open source projects to accelerate technology development and industry adoption. LFPH is launching with a mission to use open source software to help public health authorities (PHAs) around the world combat Covid-19 and future epidemics. One of the roles of LFPH is to serve as a forum for collaboration between PHAs, developers, technology companies and academics to ensure the implementation and dissemination of best practices, including privacy and security.
(tags: hse nearform covid-19 contact-tracing exposure-notification apps mobile open-source linux-foundation lfph)
Turkey Now Has Swarming Suicide Drones It Could Export – The Drive
Well, this is pretty scary — swarming autonomous kamikaze drones are actively in production right now:
It seems very possible that, in addition to providing these improved Kargu [drones] to the Turkish armed forces, STM could also seek to export them, proliferating this capability further around the world. STM has already said that it has received serious inquires about the Kargu series from at least three unnamed potential foreign customers. Turkey, as a whole, has become a powerhouse of drone development and production, employing larger types to great effect in Syria and Libya just this year. This is precisely the type of weapon we have been warning about for years now. The fact that it is already here and potentially exportable should be yet another wake-up call to the level of threat low-end drones pose to U.S. and allied forces, as well as domestic infrastructure and VIPs. “I argue all the time with my Air Force friends that the future of flight is vertical and it’s unmanned,” U.S. Marine General Kenneth McKenzie, head of U.S. Central Command, said at an event hosted by the Middle East Institute last week. “I’m not talking about large unmanned platforms, which are the size of a conventional fighter jet that we can see and deal with, as we would any other platform.” “I’m talking about the one you can go out and buy at Costco right now in the United States for a thousand dollars, four quad, rotorcraft or something like that that can be launched and flown,” he continued. “And with very simple modifications, it can make made into something that can drop a weapon like a hand grenade or something else.”
(tags: drones war terrorism ai autonomous scary kargu kerkes turkey stm)
interesting data on COVID-19 rates among school-age kids
Twitter thread:
Highest COVID-19 rate (18.6%) for household contacts of school-aged children and lowest (5.3%) for household contacts of kids 0-9; – School closure and distancing reduced rate of COVID-19 among contacts of school aged kids. What does this mean? – I believe this further supports that we need to have low rates of community transmission before we consider opening up schools; – Per this data kids 10-19 had highest rates of contacts with COVID-19; – This is scientific data, let this lead our decision.
(tags: contact-tracing south-korea schools reopening covid-19 transmission children)
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Via Zeynep Tufekci: ‘A study of an outbreak in Switzerland found that only those with plastic face-shields were infected, and everyone wearing masks was protected. Face shields may still help with source control, but masks may well also be protecting the wearer to some degree.’
(tags: switzerland covid-19 facemasks masks aerosols transmission epidemiology)
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The report, The Mental Stability of Hull, was based on interviews with hundreds of survivors. These case studies showed that people developed serious psychosomatic conditions, including involuntary soiling and wetting, persistent crying, uncontrollable shaking, headaches and chronic dizziness; men were found to indulge in heavy drinking and smoking after a raid, and prone to developing peptic ulcers. One woman was bombed out of three different houses, and watched the death of her sister and her five children. Her symptoms indicated an exceptional level of nervous collapse. Nevertheless, the conclusion from Hull was that its mental stability was nothing to worry about. The government papered over the evidence of the physical and psychological effects of being bombed and focused instead on the stories of British resolve. The propaganda film London Can Take It! reinforced the view that British people were not to be terrorised into submission. The famous photograph of a milkman picking his way through the ruins to deliver the milk was widely distributed, but it was a fake – the milkman was in fact the photographer’s assistant, wearing a white coat. The public face of the “blitz spirit” concealed the awful reality of being bombed.
(tags: coronavirus epidemic fear pandemics blitz covid-19 ptsd propaganda)
Test sensitivity is secondary to frequency and turnaround time for COVID-19 surveillance | medRxiv
this makes a whole load of sense to me — Michael Mina, one of this paper’s authors, is interviewed on TWIV, https://microbe.tv/twiv/twiv-640/ , talking about frequent, cheap, fast-turnaround COVID-19 tests, suitable for countrywide, daily testing. Less accurate than the RT-PCR swab, but good enough for this purpose
(tags: epidemiology covid-19 testing swabs rt-pcr twiv virology models papers)
Nice heatmap dataviz of Florida COVID-19 cases, over time, by age bracket
Be?v?a?n?d on Twitter: “I love this heatmap?? It represents over 100,000 individual datapoints. These are Florida COVID-19 cases, over time, by age bracket. I published open-source code to make it: https://t.co/8USY29mDDn The recent case surge is driven by 20-24-year-old Floridians. 1/N https://t.co/Pw2p9xTLaq” / Twitter
UASP makes Raspberry Pi 4 disk IO 50% faster
The more recent USB storage protocol — definitely worth using if available. ‘Without UASP, a drive is mounted as a Mass Storage Device using Bulk Only Transport (or BOT), a protocol that was designed for transferring files way back in the USB ‘Full speed’ days, when the fastest speed you could get was a whopping 12 Mbps! With USB 3.0, the BOT protocol cripples throughput. USB 3.0 has 5 Gbps of bandwidth, which is 400x more than USB 1.1. The old BOT protocol would transfer data in large chunks, and each chunk of data had to be delivered in order, without regard for buffering or multiple bits of data being able to transfer in parallel.’ (everyone’s already blogged this, but I’m lodging it here for bookmark purposes ;)
Thread on how US universities are planning to tackle COVID-19 in the fall
Michael Otsuka on Twitter: “Notre Dame is the latest example of a US university that is devoting serious planning and resources to making their campus safe for in person instruction.” This thread is full of good points on how educational institutions — not just third-level! — need to think about how to handle COVID-19 when they reopen. Key points: comprehensive testing of staff and students; contact tracing, isolation and quarantine protocols; physical distancing and mask requirements; and facilities to isolate positive staff and students and their contacts. Also, some facilities are planning to PROVIDE face coverings if students don’t have, or forget, their own. Brown University are planning to conduct “rapid testing for covid-19 for all students at regular intervals. Testing only those with symptoms will not be sufficient.” https://twitter.com/MikeOtsuka/status/1261597656373252096 — this is a point that Columbia U. Prof Vincent Racaniello, of TWIV fame (@profvrr), has been making repeatedly — pervasive mass testing is needed.
(tags: testing covid-19 reopening education universities health schools)
Wearing masks may reduce severity of COVID-19, if it is caught
Bob Wachter on Twitter: “I heard [an] interesting new theory by ID expert Monica Gandhi @UCSF: wearing masks may not only prevent disease, but – if wearer does get infected – it may be with a lower viral dose and thus cause milder disease. Some support for this from studies in mice and hamsters (below)… https://t.co/ISqtKK97ow” / Twitter
(tags: covid-19 bob-wachter virology masks facemasks theories viruses infection)
Fixers Know What ‘Repairable’ Means—Now There’s a Standard for It
European standard EN45554 ‘details ”general methods for the assessment of the ability to repair, reuse and upgrade energy-related products.” In plain English, it’s a standard for measuring how easy it is to repair stuff. It’s also a huge milestone for the fight for fair repair.’
The EU General Data Protection Regulation explained by Americans
Bashing the European Union’s General Data Protection Regulation (GDPR) seems to have become one of American activists’ favourite hobbies in the tech field. Some criticism is entirely justified. But many claims that the GDPR is “counterproductive” or “misses the point” are based on misconceptions, rather than an accurate understanding of European data protection laws. As a result, several US privacy advocates have therefore suggested alternative principles or rules… many of which, actually, have been part of EU data protection law since 1995.
(tags: gdpr privacy data-protection eu data-privacy us-politics)
The implications of silent transmission for the control of COVID-19 outbreaks | PNAS
‘In our PNAS study, we demonstrate that the majority of COVID-19 transmission is ‘silent’: from asymptomatic cases or from cases during the presymptomatic phase. Consequently, symptom-based control, such as temperature checks, is not sufficient.’
(tags: covid-19 research papers epidemiology transmission symptoms)
Why School Reopening Is Absurd and Dangerous
I love the public schools my kids attend, but I also know they can’t handle a lice outbreak on a good day and are not equipped to handle COVID on a bad one. School principals and superintendents are not epidemiologists or virologists and can’t possibly be expected to make plans like they are. So who should be making decisions? To start, the CDC. So, when the vice president of the United States says, as he did this week, that “we don’t want the guidance from the CDC to be the reason schools don’t open up,” what he’s really saying is that the government is abandoning children, parents, and all the people who work in schools.
Rethinking how we interview in Microsoft’s Developer Division
interesting new approach for interviewing being pioneered at MS’ Dev Tools division (via Niall Murphy)
(tags: via:niallm interviewing hiring microsoft work)
Rapid, inexpensive home testing for COVID-19 may get us out of this mess before a vaccine
We should welcome [rapid covid] tests, even if less accurate, and broadly adopt them for widespread community use. Here’s why: They will be cheap. Estimates are that they would cost between 1 and 5 dollars. That’s around the price of a cup of coffee. They can be done on saliva. No brain biopsy required. They can be done frequently. Every day for college students, or healthcare workers, or bus drivers? Every third day for everyone? They will answer the key question — am I contagious to others right now? Finally, and most importantly, they will answer this last question quickly. Results back in less than an hour. Anyone with a positive test can self-isolate, be reported to public health officials, participate in a contact tracing program, and be monitored for symptoms. Maybe pre-emptive antiviral therapy will prevent severe illness. We can choose to do a rapid home test any day we go to work, or to the gym, or to meet friends in a restaurant, or to attend a concert, or to pray in a house of worship, or to visit an elder loved one, or indeed partake in any activity we do in groups that now sadly may sustain the pandemic. And for those worried about lack of sensitivity, two items of reassurance. First, false negatives are less likely when people have the highest amounts of virus in saliva and respiratory secretions — and this is when they’re most contagious to others. If the test is falsely negative due to low titers of virus, it may not matter very much. Second, this modeling study finds that the frequency of testing is the key determinant of how well a broad testing strategy will limit the spread of the virus. It’s even more important than test sensitivity, and evidence that imperfect testing is better than no testing at all.
(tags: testing covid-19 pcr rt-pcr false-positives false-negatives viruses)
Understand Wi-Fi 4/5/6/6E (802.11 n/ac/ax)
Some excellent advice regarding the currently available wifi devices out there, 802.11ac, 4×4 MIMO, beamforming, and DFS channels. Top recommendations are the Ubiquiti nanoHD AP and the Netgear R7800
(tags: wifi 802.11n 802.11ac networking wireless home mimo mu-mimo dfs)
????? (revenge bedtime procrastination)
“a phenomenon in which people who don’t have much control over their daytime life refuse to sleep early in order to regain some sense of freedom during late night hours” Welcome to my life. (aka parenting)
(tags: day night life kids parenting procrastination bedtime sleep china)
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According to this new [analysis of the latest generation of climate models], led by scientists at the CSIRO and [Australian] Bureau of Meteorology, the worst-case scenario could see Australia warm up to 7°C above pre-industrial levels by the end of the century. On average, the results from 20 models show a warming of 4.5°C, with a range of between 2.7°C and 6.2°C. [….] Another profoundly significant result is buried 16 pages deep into the paper. The scientists show that this revision now means that 2°C of global warming is likely to be reached sometime around 2040 based on our current high-emissions trajectory. The implications of this are unimaginable – we may witness planetary collapse far sooner than we once thought.
This is horrific, if those are solid estimates… those warming levels will mean Australia (and parts of the rest of the world) becomes pretty much uninhabitable. Weak bits floppy disc protection
Amazing anti-piracy scheme from the BBC Micro era, devised by Simon Hosler of Sherston Software: “Weak” or “Flaky” bits, caused by “a weak signal or non-existent magnetic signal on the disc surface. You might also see the term no-flux area (NFA), which is the same as a non-existent signal. Weak bits are almost always a non-existent signal, as opposed to a weak signal. The flaky nature of weak bits actually comes out of the drive electronics: when there are no clear flux changes, the drive just amplifies harder until it starts seeing and signalling ghosts within the noise.” Simon Hosler wrote: “Soft lock (was what we called it) was actually my system, so what I remember… This came about because I lived next door to an electronics geek! So break the write data line of the parallel disk cable. Add a bit of electronics to this line. (thank you Mike) Most of the time this electronics does nothing – lets the data go through as normal. If you turn it on (I think I did this through the serial port) and write to a single sector – it would count the bits going through say 256 – and then stop the next 256 bits going through”
(tags: bbc-micro microcomputers history copy-protection anti-piracy piracy weak-bits hardware hacks simon-hosler)
The Center for Land Use Interpretation
More than 30 uranium disposal cells have been constructed over the last 25 years, primarily to contain radioactive contamination from decommissioned uranium mills and processing sites. They are time capsules, of sorts, designed to take their toxic contents, undisturbed, as far into the future as possible. Uranium disposal cells are unusual constructions because they are built to last far beyond the lives of most engineered structures, to isolate their radioactive contents from the environment for hundreds of years. They are generally low geometric mounds, sometimes as high as a hundred feet tall, covering a few acres or as much as a half mile, and composed of layers of engineered soil and gravels designed to shed rainwater and limit erosion. […] The contents are not considered high-level radioactive waste, like spent fuel from nuclear reactors. That material has yet to find a permanent home. What these cells contain is radioactive tailings from uranium processing sites, as well as the demolished buildings and apparatus from the mills themselves. The amount of radioactivity in these cells varies, but is generally considered harmful to people if exposure takes place over sustained periods. Most of the radiation comes from uranium 238, which has a half life of 4.47 billion years, nearly the age of the earth itself.
(tags: nuclear uranium history waste toxic-waste radioactivity u-238 radioactive structures land-use)