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Justin's Linklog Posts

Links for 2021-01-18

Links for 2021-01-14

  • Seasonality of Respiratory Viral Infections | Annual Review of Virology

    tl;dr: temperature, humidity, vitamin D are all important:

    The seasonal cycle of respiratory viral diseases has been widely recognized for thousands of years, as annual epidemics of the common cold and influenza disease hit the human population like clockwork in the winter season in temperate regions. Moreover, epidemics caused by viruses such as severe acute respiratory syndrome coronavirus (SARS-CoV) and the newly emerging SARS-CoV-2 occur during the winter months. The mechanisms underlying the seasonal nature of respiratory viral infections have been examined and debated for many years. The two major contributing factors are the changes in environmental parameters and human behavior. Studies have revealed the effect of temperature and humidity on respiratory virus stability and transmission rates. More recent research highlights the importance of the environmental factors, especially temperature and humidity, in modulating host intrinsic, innate, and adaptive immune responses to viral infections in the respiratory tract. Here we review evidence of how outdoor and indoor climates are linked to the seasonality of viral respiratory infections. We further discuss determinants of host response in the seasonality of respiratory viruses by highlighting recent studies in the field.

    (tags: infection viruses colds flu covid-19 seasonality diseases)

Links for 2021-01-13

  • Endemic SARS-CoV-2 will maintain post-pandemic immunity

    This article in _Nature Reviews Immunology_ suggests that "SARS-CoV-2 is likely to become the fifth endemic common cold virus, causing largely asymptomatic infections."

    Endemic SARS-CoV-2 will ensure maintenance of seroprevalence and mucosal immunity in the population, which will increase over time in new generations. As such, most infected individuals will ultimately endure a largely asymptomatic or mild course of disease, although similarly to the other common cold HCoVs, SARS-CoV-2 may cause fatalities in extremely vulnerable elderly or immunocompromised individuals. SARS-CoV-2 mutants will arise as already reported, but new variants will unlikely differ sufficiently to escape established immunity. Cross-reactive immunity, critically boosted by natural reinfections, should conserve good levels of population protection also against new variants, thereby preventing the occurrence of severe disease, including in the vulnerable. Therefore, we predict that the need for large-scale vaccination programmes will be transient until an endemic state for SARS-CoV-2 is reached.

    (tags: sars-cov-2 covid-19 diseases immunology nature)

Links for 2021-01-11

Links for 2021-01-10

  • Derctuo

    Kragen's followup to Dercuano:

    a book of notes on various topics, mostly science and engineering with some math, from the first year of the COVID-19 pandemic, 02020 CE.  Its primary published form is a gzipped tarball of 9MB of HTML files and sources, although there’s also an inferior PDF version of about 1000 pages for reading on hand computers or printing. It uses a page size slightly smaller than standard for improved readability on hand computers. [....] It contains some novel discoveries, but some of it is just my notes from exploring the enormous feast of knowledge now available on the internet to anyone who takes the time to taste of it, and some other parts are explorations that didn’t pan out — left here only as a cautionary tale to the next explorer. There are lots of notes in here that aren’t “finished” in the usual sense; they end in the middle of a sentence, or say “XXX”, or have a note in them that the foregoing is wrong in such-and-such a way.  But I am publishing the final version of Derctuo today.  I might make future versions of some of these notes, but not of Derctuo itself.

    (tags: derctuo kragen notes books reading essays)

  • A large scale analysis of hundreds of in-memory cache clusters at Twitter | USENIX

    Modern web services use in-memory caching extensively to increase throughput and reduce latency. There have been several workload analyses of production systems that have fueled research in improving the effectiveness of in-memory caching systems. However, the coverage is still sparse considering the wide spectrum of industrial cache use cases. In this work, we significantly further the understanding of real-world cache workloads by collecting production traces from 153 in-memory cache clusters at Twitter, sifting through over 80 TB of data, and sometimes interpreting the workloads in the context of the business logic behind them. We perform a comprehensive analysis to characterize cache workloads based on traffic pattern, time-to-live (TTL), popularity distribution, and size distribution. A fine-grained view of different workloads uncover the diversity of use cases: many are far more write-heavy or more skewed than previously shown and some display unique temporal patterns. We also observe that TTL is an important and sometimes defining parameter of cache working sets. Our simulations show that ideal replacement strategy in production caches can be surprising, for example, FIFO works the best for a large number of workloads.

    (tags: caching memcached memory twitter usenix via:marc-brooker)

  • Is there a tool that tells you which IAM actions to allow if you give it an API operation? : aws

    'For example, say I want to allow an IAM role to aws s3 sync to a given S3 bucket. Is there a tool that will tell me the list of actions to permit on the bucket, if I input that command to the tool?' tl;dr: nope there is not. Good list of links to related tools to ameliorate the IAM shitfest though

    (tags: iam aws permissions security apis)

  • The PHIA probability yardstick

    the UK government's official terminology to clearly describe the probability of events occurring, ranging from "REMOTE CHANCE" to "ALMOST CERTAIN"

    (tags: chance probability terminology words uk phia odds)

  • Mason, Thomas Holmes (1877-1958)

    My illustrious great-grandfather:

    Mason was a keen cyclist; his tours through the Irish countryside as a youth, as well as his interest in photography from the age of twelve (he would take over 20,000 pictures by his death), led him to the study of the natural world and Irish archaeology. This culminated in his publication of The islands of Ireland: their scenery, people, life and antiquities (1936), visually recording the minutiae of Irish folk life and the natural beauty of the island landscapes. Mason did not restrict his interests to any one discipline and was involved in a multifarious range of organisations: member of the Dublin Field Club, one-time president of the Irish Society for the Protection of Birds, member of the Dublin Zoological Council (serving as honorary vice-president from 1952), member and president (1926) of the Photography Society of Ireland, member of the Geographical Society of Ireland, and member of the National Monuments Council as well as president (1951) of An Taisce. He was also president of the Dublin Mercantile Association (1923) and the Dublin Rotary Club and a fellow of the RSAI. He was elected MRIA (1931) and contributed numerous articles to the Academy's Transactions and Proceedings on subjects ranging from the history of the optical profession in Dublin to Celtic archaeology. Mason provided meteorological information to Irish newspapers from his home observatory at 39 Kenilworth Square before the establishment of the Irish meteorological service (1936). His other interests included Irish moths as well as Irish lantern slides, on which he published Catalogue of photographic lantern slides of Irish scenery and antiquities [n.d.] and Catalogue of lantern slides of Irish antiquities (1928). Mason was the seventh member of his family to be made an honorary freeman of the city of Dublin (29 April 1903), one of the last such hereditary appointments. His wife Margaret Evelyn, whom he married c.1909, was a fellow presbyterian. Three of his four sons succeeded him in the family business, which celebrated its bicentenary in 1980 and traded into the third millennium. He died on 12 February 1958, leaving his library to the Old Dublin Society and TCD.

    (tags: family thomas-mason history ireland archaeology photography)

Links for 2021-01-08

Links for 2021-01-07

  • Practical tips for if you test positive for COVID-19

    good video from MedCram ("Evidence based updates on COVID-19 and CME for clinicians.") -- I don't need it -- yet -- but bookmarking just in case...

    Practical tips from Dr. Seheult if you test positive for COVID-19: - Use of a pulse oximeter at home; - Who gets monoclonals? - Immune boosting vitamins: D, NAC, C, Quercetin, Zinc; - The data on sleep (& melatonin); - Data on core temp. elevation (Sauna etc)

    (tags: medcram medicine covid-19 treatment immunity)

Links for 2021-01-06

Links for 2020-12-31

  • Derek Lowe on the UK authorities' plan to spread out the two doses of the Pfizer/BioNTech vaccine

    'The UK government is thus running a real-time experiment on its population in the hopes that the benefits of a first dose of its available vaccines (AZ/Oxford, Pfizer/BioNTech) will outweigh the risks of then messing with the dosing schedule. The horrible part is that there’s a good case to be made that running this big experiment (and taking on the risk of lowering the overall effect of the two-dose schedule) is still the right decision. Things are bad. But don’t pretend it’s not an experiment, or that we know what the outcome will be. This is a desperation move, and it’s a terrible thing that such a strategy has made it to the top of the list. I hope it works.'

    (tags: vaccines vaccination covid-19 uk dosing)

Links for 2020-12-28

  • I'm a consultant in infectious diseases. 'Long Covid' is anything but a mild illness | Long Covid | The Guardian

    With the excitement of the Covid vaccine’s arrival, it may be easy to forget and ignore those of us with “long Covid”, who are struggling to reclaim our previous, pre-viral lives and continue to live with debilitating symptoms. Even when the NHS has managed the herculean task of vaccinating the nation, Covid-19 and the new mutant variants of the virus will continue to circulate, leaving more people at risk of long Covid. Data from a King’s College London study in September suggested as many as 60,000 people in the UK could be affected, but the latest statistics from the Office for National Statistics suggest it could be much higher.
    (via Shane Dempsey)

    (tags: via:sdempsey long-covid covid-19 health medicine)

  • Characterizing Long COVID in an International Cohort: 7 Months of Symptoms and Their Impact | medRxiv

    'From a cohort of 3762 Long COVID respondents, probability of symptoms lasting >35 weeks was 91.8%'; 'Most frequent lingering symptoms reported after 6 months were: fatigue 77.7%, post-exertional malaise* 72.2% and cognitive dysfunction 55.4%.'

    (tags: long-covid covid-19 health medicine papers)

  • The carbon footprint sham

    BP created the concept of a 'carbon footprint' as a devious, manipulative PR tactic:

    A few years after BP began promoting the “carbon footprint,” MIT researchers calculated the carbon emissions for “a homeless person who ate in soup kitchens and slept in homeless shelters" in the U.S. That destitute individual will still indirectly emit some 8.5 tons of carbon dioxide each year. “Even a homeless person living in a fossil fuel powered society has an unsustainably high carbon footprint,” said Stanford’s Franta. “As long as fossil fuels are the basis for the energy system, you could never have a sustainable carbon footprint. You simply can’t do it.”

    (tags: carbon co2 bp emissions climate-change pr)

Links for 2020-12-23

  • "Glutamate plumes" as a potential origin for migraines

    Mice that get migraines have helped scientists in the US to uncover what might be going on in the more than 10 per cent of us who suffer from the condition. What K.C. Brennan at the University of Utah has done is to make a genetic change in his mice, so they mimic the make-up of one group of humans who suffer regular migraines. By watching the brains of these animals, they’ve found that, periodically, surges appear of an excitatory nerve signal called glutamate. This, they speculate, causes overstimulation of the nearby nerve cells, starting the neurological equivalent of a Mexican wave that ripples across the brain. As it does so, it activates pain pathways that cause the ensuing headache.

    (tags: glutamate neurotransmitters neurology brains health medicine mice migraines headaches)

Links for 2020-12-17

  • Rocky Flats

    Absolutely bananas Twitter thread -- it is frankly miraculous that they didn't have multiple criticality incidents on their hands. TIL about "infinity rooms":

    'They made plutonium "pits" for nuclear bombs, either from new plutonium sources or reprocess parts of old bombs, from 1957 until 1988. In 1988, the EPA investigated the site, shrieked in horror, and shut the place down. the DOE stuck their fingers in their ears and went LA LA LA DON'T WANNA DEAL WITH IT for about five years afterward, but finally started cleanup in '94. Among the tasks: cleaning 13 "infinity rooms" - areas so radioactive that plant instruments went off the scale, and were just sealed in place. One had been welded shut and abandoned as far back as '72. One had been piled full of contaminated equipment and filled with concrete. US Gov: your task is finding the 1,100 pounds of plutonium that somehow became lost in ductwork, drums and industrial gloveboxes. The amount of missing plutonium at Rocky Flats is enough to build 150 Nagasaki strength bombs. "Occasionally you'd feel a drip on your head and you'd be contaminated with plutonium nitrate," DeMaiori said."'

    (tags: infinity-rooms horror military-industrial-complex us-politics nuclear nuclear-weapons plutonium environment history bombs epa doe)

  • How to Send SMS Messages with Google Sheets and your Android Phone - Digital Inspiration

    Particularly impressive demo of MIT AppInventor, which lets you build an Android app with block-based GUI programming

    (tags: appinventor apps android mit coding blocks gui sms google-sheets texting)

Links for 2020-12-16

Links for 2020-12-14

Links for 2020-12-09

Links for 2020-12-08

  • Amazon, Amex to Fund Software Developers in New GitHub Program - Bloomberg

    'Amazon.com Inc., American Express Co., Daimler AG and Stripe Inc. are among those joining a new GitHub program that will let companies directly fund open-source projects and software developers that are key to their businesses.' interesting

    (tags: github funding open-source oss work software)

  • Ventilation | CDC

    This is significant -- the CDC is _finally_ detailing mitigation strategies against airborne SARS-CoV-2.

    When indoors, ventilation mitigation strategies help to offset the absence of natural wind and reduce the concentration of viral particles in the indoor air. The lower the concentration, the less likely some of those viral particles can be inhaled into your lungs; contact your eyes, nose, and mouth; or fall out of the air to accumulate on surfaces. Protective ventilation practices and interventions can reduce the airborne concentration, which reduces the overall viral dose to occupants. Below is a list of ventilation interventions that can help reduce the concentration of virus particles in the air, such as SARS-CoV-2. They represent a list of “tools in the mitigation toolbox,” each of which can be effective on their own.  Implementing multiple tools at the same time is consistent with CDC mitigation strategies and increases overall effectiveness. These ventilation interventions can reduce the risk of exposure to the virus and reduce the spread of disease, but they will not eliminate risk completely.

    (tags: covid-19 advice cdc best-practices ventilation air air-quality sars-cov-2)

  • dropbox/setsum

    Via Robert Escriva - 'the set-based checksum algorithm we made. Add items in any order and still get the same checksum. Union two independently created sets and get the same result as having done it as one iteration.'

    (tags: checksums hashing dropbox sums summarising algorithms streaming)

Links for 2020-12-04

Links for 2020-12-03

  • Hammerspoon

    'a tool for powerful automation of OS X. At its core, Hammerspoon is just a bridge between the operating system and a Lua scripting engine. What gives Hammerspoon its power is a set of extensions that expose specific pieces of system functionality, to the user. You can write Lua code that interacts with OS X APIs for applications, windows, mouse pointers, filesystem objects, audio devices, batteries, screens, low-level keyboard/mouse events, clipboards, location services, wifi, and more.' (via Tony Finch)

    (tags: via:fanf automation osx mac lua scripting hammerspoon)

Links for 2020-12-01

Links for 2020-11-26

Links for 2020-11-25

  • Gnome launched into space in a real-life reenactment of a Half Life 2 achievement

    A new achievement called "Gnome Alone" was added to [Half-Life 2: Episode Two, Half-Life: Alyx, and Left 4 Dead 2], and the description sums up exactly what's going on. "If you are reading this achievement, Gabe Newell has successfully launched Gnome Chompski into space. If you did not also receive the achievement 'Manufacturing Ascent', Newell has abandoned his plans to shoot Noam Chomsky into space." ...There's an Amelie-inspired achievement for picking up the gnome at the start of [Half Life 2: Episode Two] and bringing it all the way to the rocket at White Forest Base, an arduous task involving lots of item juggling and repeated cramming of the gnome into a crevice in Episode Two's muscle car. Similar challenges made their way into Alyx and Left 4 Dead 2 as well.

    (tags: garden-gnomes gnomes funny noam-chomsky achievements games half-life history gabe-newell rockets space)

Links for 2020-11-24

  • Home Assistant Data Science

    Great feature:

    The Home Assistant Data Science portal is your one stop shop to get started exploring the data of your home. We will teach you about the data that Home Assistant tracks for you and we'll get you up and running with Jupyter Lab, a data science environment, to explore your own data.

    (tags: docs data home-assistant iot data-science graphs o11y home han)

  • Excel error causes 1,500 deaths

    Excerpted from _Does contact tracing work? Quasi-experimental evidence from an Excel error in England_: 'we find 120,000 COVID-19 cases & 1,500 deaths linked to those cases that were not referred to contact tracing in time. This represents ~20% of all new COVID19 cases [in England] during weeks 39-44.' Twitter thread: https://twitter.com/fetzert/status/1331139902965227520

    (tags: excel fail public-health contact-tracing england nhs covid-19 deaths papers)

  • misleading reliance on pointing to "household transmission" for COVID-19 in Ireland

    This article is a perfect example. It's headlined: "Virus spread: How a single household transmission led to 46 Covid-19 cases"

    A team of public health specialists in the midlands traced how a case of household transmission led to 26 cases of Covid-19 in a manufacturing plant and a further 20 cases in other households, a nursing home and a school. The first case, or “index case” they became aware of was a woman who worked in a manufacturing plant. Household transmission of the virus occurred when a person she was living with, who had acquired Covid in a pub, passed the virus to her.
    So in other words -- the true index case was the person in the pub, or at the very least, her housemate who picked up COVID-19 in the pub, and this was a case where the pub was the initial cluster location, leading to 47 further cases. But for some reason, the article chooses "household transmission" as the headline...

    (tags: pubs restaurants covid-19 safety epidemiology ireland contact-tracing public-health households transmission)

  • What Facebook Fed the Baby Boomers - The New York Times

    The feed goes on like this — an infinite scroll of content without context. Touching family moments are interspersed with Bible quotes that look like Hallmark cards, hyperpartisan fearmongering and conspiratorial misinformation. Mr. Young’s news feed is, in a word, a nightmare. I know because I spent the last three weeks living inside it.

    (tags: grim-meathook-future facebook newsfeed america nytimes)

Links for 2020-11-24

Links for 2020-11-19

Links for 2020-11-18

  • Pavement's "Harness Your Hopes" And Spotify's Algorithm - Stereogum

    Songs emerging from obscure back-catalogue status thanks to glitches in the "Autoplay" algorithm:

    Spotify appears to have the capacity to create “hits” without even realizing it. When it comes to Galaxie 500, “there’s just no way this would have happened before this flip in the Spotify plays,” Krukowksi notes. “And now we’re becoming identified as a band with that song, because if they learn about the band through Spotify, that’s what they’re hearing. So it becomes, like, our emblem.”

    (tags: technology music spotify streaming galaxie-500 pavement autoplay)

Links for 2020-11-16

  • OSHA issues ventilation guidance to workplaces for airborne SARS-CoV-2

    OSHA issues ventilation guidance to workplaces for airborne #SARSCoV2: - HVAC systems should be fully functional; - Prevent personal fans from blowing air from one worker to another; - Use HVAC filters w/MERV rating 13 or higher; - Increase HVAC's outdoor air intake; - Open windows/sources of fresh air; - Be sure exhaust air isn't pulled back into the building from HVAC air intakes or open windows; - Use portable HEPA fan/filtration to increase clean air; - Restrooms fans should operate max capacity, and remain on.
    These are all eminently sensible. Now to see if anything equivalent happens on this side of the pond.

    (tags: aerosols covid-19 airborne diseases sars-cov-2 transmission air fans hvac air-conditioning workplaces work)

  • Can’t open apps on macOS: an OCSP disaster waiting to happen | CryptoHack Blog

    Finally, a good take on Apple's OCSP crapfest over the past weekend.

    If Apple’s OCSP check was built to soft-fail [which is apparently the case], then why did apps hang when the OCSP Responder was down? Probably because this was actually a different failure case: the OCSP Responder was not completely down, it was performing badly. Due to the load added by millions of users worldwide upgrading to macOS “Big Sur”, Apple’s servers slowed to a crawl, and although they weren’t properly answering OCSP queries, they were working just enough that the soft-fail didn’t trigger.
    IMO -- this is a big fail by Apple. Network callouts to perform OCSP checks on app startup are a critical case where a Hystrix-level infrastructure of timeouts and short-circuits were appropriate to fail safely in as many situations as possible. The article goes on:
    By adding several mundane failure modes to the verification process, OCSP spoils any cryptographic elegance the code signing and verifying process has. While OCSP is also widely used for TLS certificates on the internet, the large number of PKI certificate authorities and relaxed attitude of browsers means that failures are less catastrophic. Moreover, people are accustomed to seeing websites become unavailable from time to time, but they don’t expect the same from apps on their own devices. macOS users were alarmed at how their apps could become collateral damage for an infrastructure issue at Apple. Yet this was an inevitable outcome arising from the fact that certificate verification depends on external infrastructure, and no infrastructure is 100% reliable. Scott Helme also has concerns about the power that Certificate Authorities gain when certification revocation actually works effectively. Even if you aren’t bothered about the potential for censorship, there will be occasional mistakes and these must be weighed against the security benefits. As one developer discovered when Apple mistakenly revoked his certificate, the risk of working within a locked down platform is that you may get locked out.

    (tags: apple ocsp fail fail-safe hystrix osx macos)

Links for 2020-11-13

  • Risk Assessment and Management of COVID-19 Among Travelers Arriving at Designated U.S. Airports, January 17–September 13, 2020 | MMWR

    MMWR from the CDC on passenger entry screening at US airports (via Anthony Staines):

    Passenger entry screening was resource-intensive with low yield of laboratory-diagnosed COVID-19 cases (one case per 85,000 travelers screened). Contact information was missing for a substantial proportion of screened travelers in the absence of manual data collection. What are the implications for public health practice? Symptom-based screening programs are ineffective because of the nonspecific clinical presentation of COVID-19 and asymptomatic cases. Reducing COVID-19 importation has transitioned to enhancing communication with travelers to promote recommended preventive measures, strengthening response capacity at ports of entry, and encouraging predeparture and postarrival testing. Collection of contact information from international air passengers before arrival would facilitate timely postarrival management when indicated.

    (tags: screening travel air air-travel airports via:astaines cdc mmwr covid-19)

  • Inky Impression

    Wow, this looks spectacular!

    5.7", 600 x 448 pixel 7 colour electronic paper (ePaper / eInk / EPD) display for Raspberry Pi. plenty of screen real estate for text or graphics. The low power consumption e-paper display is crisp and readable in bright sunlight and the image will persist when unpowered. In a first for the Inky series, we've also added four tactile buttons on the back, so you can control what's on the screen without the need for extra hardware. But the best bit is that this time you get seven whole colours to play with, which means this Inky is very suitable for displaying graphics, drawings or art - we've found pixel art, panels from comics and retro video game art look particularly good.

    (tags: e-ink displays raspberry-pi hacking video devices e-paper)

  • Charles proxy for web scraping

    wow, Charles is nifty. must give it a go next time I'm scraping something

    (tags: scraping mitm charles web http proxies web-scraping automation)

Links for 2020-11-13

  • Risk Assessment and Management of COVID-19 Among Travelers Arriving at Designated U.S. Airports, January 17–September 13, 2020 | MMWR

    MMWR from the CDC on passenger entry screening at US airports (via Anthony Staines):

    Passenger entry screening was resource-intensive with low yield of laboratory-diagnosed COVID-19 cases (one case per 85,000 travelers screened). Contact information was missing for a substantial proportion of screened travelers in the absence of manual data collection. What are the implications for public health practice? Symptom-based screening programs are ineffective because of the nonspecific clinical presentation of COVID-19 and asymptomatic cases. Reducing COVID-19 importation has transitioned to enhancing communication with travelers to promote recommended preventive measures, strengthening response capacity at ports of entry, and encouraging predeparture and postarrival testing. Collection of contact information from international air passengers before arrival would facilitate timely postarrival management when indicated.

    (tags: screening travel air air-travel airports via:astaines cdc mmwr covid-19)

Links for 2020-11-12

  • Covid Winter is Coming. Could Humidifiers Help? | WIRED

    Add humidity to the list:

    after three months of data crunching, they found that the most powerful correlation between national numbers of daily new coronavirus cases and daily Covid-19 deaths was indoor relative humidity. Even controlling for dozens of other factors, the data showed that as indoor relative humidity went up during the summer months in the northern hemisphere, deaths plummeted. In the southern hemisphere, the opposite was true—as humidity fell during those nations’ winter months, deaths began to climb. “It’s so powerful, it’s crazy,” says [Stephanie] Taylor. That work has not yet been published. But Taylor believes it’s the strongest evidence yet that humidity needs to be as much a part of the conversation about containing Covid-19 as is discussion of ventilation, masks, and hand hygiene. “It’s hard to prioritize one intervention over another; we need all of them,” says Taylor. “Humidifiers aren’t a replacement for masks or social distancing or ventilation. But when you have more humidification, it enhances all these other things we’re already doing.” At higher humidities, respiratory particles grow faster and fall to the ground earlier, so there’s a better chance that staying 6 feet apart from infectious people really will dilute how many bits of their aerosolized virus you might happen to inhale. In a recent modeling study, Japanese researchers found that air with 30 percent relative humidity can carry more than twice the number of infectious aerosols, compared to air with relative humidity levels of 60 percent or higher. That also means masks are more likely to block more of the particles coming out of people’s noses and mouths, because they tend to be better at trapping bigger particles than smaller ones. And it means that air purifiers (even cheap, DIY ones) will filter out a larger proportion of potentially infectious particles.

    (tags: covid-19 aerosols humidity humidifiers air air-quality health infection)

  • 50 beautiful Irish crafts to buy, and the people who make them

    so many good things here

    (tags: crafts art ireland irish gifts xmas)

Links for 2020-11-09

Links for 2020-11-09

Links for 2020-11-03

  • COVID-19 IFR is estimated at 0.97%

    Florian Krammer on Twitter: "Our NYC serosurvey paper is now out in Nature: if extrapolated to the NYC population we found [more than] 1.7 million infected and IFR at 0.97" That's high! Nearly 1 in 100.

    (tags: ifr covid-19 florian-krammer mortality deaths pandemics)

  • Fault in NHS Covid app meant thousands at risk did not quarantine

    Somebody, somewhere, will have died needlessly due to this bug.

    The root of the error, the Guardian has learned, was a decision to incorporate a measure of “infectiousness” into the app’s code. While the app was undergoing testing in the Isle of Wight, it used a simple metric that recommended isolation for anyone who had been in contact – closer than 2 metres – with a potentially infectious person for 15 minutes or more in a single day. But shortly before the app was launched nationally, it was updated to account for the fact that people are most infectious shortly after their symptoms show. The maths was changed so that people outside that period of peak infectiousness counted for just two-fifths of the risk. Since that meant the overall score was likely to be lower, the intention was to reduce the risk threshold correspondingly to ensure that someone of maximum infectiousness would need just three minutes of contact before they triggered an alert. But that change never happened, and as a result, users were only told to isolate if they had spent 15 minutes close to a very infectious person, or nearly 40 minutes near someone who was pre-symptomatic but still thought to be shedding the virus. The error was only discovered when a new version of the contact-tracing app, which can better account for exposures at mid-range (over a metre away) was created. The unfeasibly high risk score also explained another problem plaguing the app: “ghost notifications” warning users that they may have been exposed to someone with Covid, but which never resulted in advice to isolate. The app’s initial advice to users was that these notifications could be safely ignored, since they reflected a contact below the risk threshold; now that the NHS risk threshold is known to have been artificially low, one insider said, it is likely that the vast majority of those ghost notifications should in fact have been advice to self-isolate.

    (tags: bluetooth nhs bugs failure ble covid-19 uk)

Links for 2020-11-02

  • I Lived Through Collapse. America Is Already There. | by Indi Samarajiva

    In the last three months America has lost more people than Sri Lanka lost in 30 years of civil war. If this isn’t collapse, then the word has no meaning. You probably still think of Sri Lanka as a shithole, though the war ended over a decade ago and we’re (relatively) fine. Then what does that make you? America has fallen. You need to look up, at the people you’re used to looking down on. We’re trying to tell you something. I have lived through collapse and you’re already there. Until you understand this, you only have further to fall.

    (tags: collapse usa politics columbo sri-lanka history civil-war)

Links for 2020-10-27

Links for 2020-10-23

Links for 2020-10-22

  • One in 20 people likely to suffer from ‘Long COVID’

    Overall, the team found that while most people with COVID-19 reported being back to normal in 11 days or less, around one in seven (13.3%, 558 users) had symptoms lasting for at least 4 weeks, with around one in 20 (4.5%, 189 users) staying ill for 8 weeks and one in fifty (2.3%, 95 users) suffering for longer than 12 weeks.  Extrapolating out to the general UK population, which has a different age and gender makeup compared with the COVID Symptom Study app users, the team estimated that around one in seven (14.5%) of people with symptomatic COVID-19 would be ill for at least 4 weeks, one in 20 (5.1%) for 8 weeks and one in 45 (2.2%) for 12 weeks or more.  
    (via Valen)

    (tags: via:valen long-covid covid-19 health)

  • intercom/lease

    'Lease is a general DynamoDB-based lease implementation, ideal for long-lived work items, with coarse-grained leases', in Go, by the inimitable ex-Swrver Rob Clancy

    (tags: golang go leases dynamodb aws locking libraries open-source distcomp)

Links for 2020-10-21

  • q - Text as Data

    'a command line tool that allows direct execution of SQL-like queries on CSVs/TSVs (and any other tabular text files). q treats ordinary files as database tables, and supports all SQL constructs, such as WHERE, GROUP BY, JOINs etc. It supports automatic column name and column type detection, and provides full support for multiple encodings.' Awesome!

    (tags: csv database sql cli data tools unix tsv)

Links for 2020-10-20

  • r/Ireland Christmas Market

    The denizens of r/Ireland pipe up with their favoured sources of online gifts for Xmas

    (tags: reddit ireland shopping christmas gifts shops)

  • WHO: US, Europe need to get better at quarantining - Business Insider

    Now _this_ is a good point.

    Maria Van Kerkhove, the WHO's technical lead for COVID-19 said during the meeting Monday that she's had lots of friends and family asking her in recent days what, exactly, quarantine is. Essentially, it's complete isolation from other people, including those you'd normally live with and breathe around, to the fullest extent possible.  "That means not going to work," Van Kerkhove said. "It means not going to the grocery store. It means not socializing with friends. It means not having people over at your home." Ideally, quarantining is a disease-fighting measure that is supported by local health programs and government support that can allow people to continue making a living and feeding their families while in quarantine, she said. 

    (tags: quarantine covid-19 infection isolation pandemics public-health)

Links for 2020-10-14

  • RangeTherapy

    Muxsan are a Dutch company selling range extension kits for Nissan Leaf EVs, increasing their range from a Gen 1 Leaf's 110km to a typical 238km; 440km is the max. 'The extension pack consists of many Lithium-ion cells [NMC], which are of the highest quality, bound by aluminum casing into modules and each module comes with a German built Battery Management System [BMS].'

    (tags: nissan cars leaf driving evs muxsan batteries hacking)

Links for 2020-10-12

  • The top 100 BBCMicroBot tweets

    these are _amazing_. Huge respect to all the contributors who wrote these great little demos-in-a-tweet

    (tags: demoscene demos bbc bbc-micro coding)

  • How Brain Fog Plagues Covid-19 Survivors - The New York Times

    “It scares me to think I’m working,” Ms. Mizelle, 53, said. “I feel like I have dementia.” It’s becoming known as Covid brain fog: troubling cognitive symptoms that can include memory loss, confusion, difficulty focusing, dizziness and grasping for everyday words. Increasingly, Covid survivors say brain fog is impairing their ability to work and function normally. “There are thousands of people who have that,” said Dr. Igor Koralnik, chief of neuro-infectious disease at Northwestern Medicine in Chicago, who has already seen hundreds of survivors at a post-Covid clinic he leads. “The impact on the work force that’s affected is going to be significant. Scientists aren’t sure what causes brain fog, which varies widely and affects even people who became only mildly physically ill from Covid-19 and had no previous medical conditions. Leading theories are that it arises when the body’s immune response to the virus doesn’t shut down or from inflammation in blood vessels leading to the brain. Confusion, delirium and other types of altered mental function, called encephalopathy, have occurred during hospitalization for Covid-19 respiratory problems, and a study found such patients needed longer hospitalizations, had higher mortality rates and often couldn’t manage daily activities right after hospitalization. But research on long-lasting brain fog is just beginning. A French report in August on 120 patients who had been hospitalized found that 34 percent had memory loss and 27 percent had concentration problems months later.

    (tags: brain-fog covid-19 sequelae inflammation side-effects)

Links for 2020-10-08

Links for 2020-10-07

Links for 2020-10-06

  • Marc Bevand's cases-vs-deaths graph for Florida

    "deaths can lag up to 1 month after cases" -- clear dataviz. Going to be sadly very relevant in Ireland in about a month's time

    (tags: ireland covid-19 pandemic via:firefoxx66)

  • Timeline of COVID -19 and Vietnam policy actions at a glance

    Vietnam’s policy actions regarding COVID -19 are recapped in a timeline together with the outbreak’s movement and in context with other Asian countries from the start of 2020 to early of August 2020. Quick and decisive actions including touch control on travelling, intensive quarantine for overseas arrivals and suspected cases, massive testing and aggressive contract tracing, sealing off virus hot-spots and timely communication from very early on are considered to have contributed to Vietnam’s performance given its vulnerable position to China, a population of 100 million people and a comparatively under-developed healthcare system.

    (tags: vietnam lockdown pandemics covid-19 public-health)

Links for 2020-10-05

  • Dr Zoë Hyde's latest Twitter thread on kids and COVID-19

    With an Aussie perspective -- Dr. Hyde works in Perth. 'Summary: further evidence children & adults are equally susceptible & equally likely to transmit; school clusters are increasing; precautions needed in schools.'

    (tags: schools education covid-19 transmission)

  • Selling Our Genes: Government inaction allowing private sector to take control of our DNA

    Genuity Science, the main company involved in DNA sequencing in Ireland, has at least 25 links to facilities around Ireland. These include funding and collaborations with major hospitals, universities, research facilities and charities. A collaboration agreement signed between Genuity Science and UCD is “restrictive”, according to an academic expert, though Genuity Science Ireland disagree with this assessment. We have the full details in this breakout article. Hospital clinicians have become “agents of a company” due to the nature of agreements in place, according to experts. Researchers are making “the best of the situation” in Ireland by working with the private sector but most would prefer a public system due to data access concerns. Lack of Government policy and adequate regulation means that private companies have no limit on how long they have exclusive access to the data they collect from Irish patients. Researchers and patient representatives are concerned about a potential erosion of trust in genetics research in Ireland.

    (tags: genomics genuity genetics ucd gmi ireland data-privacy data-protection research)

Links for 2020-10-01

  • WebPlotDigitizer

    Extract data from plots, images, and maps:

    It is often necessary to reverse engineer images of data visualizations to extract the underlying numerical data. WebPlotDigitizer is a semi-automated tool that makes this process extremely easy: Works with a wide variety of charts (XY, bar, polar, ternary, maps etc.) Automatic extraction algorithms make it easy to extract a large number of data points Free to use, opensource and cross-platform (web and desktop) Used in hundreds of published works by thousands of users Also useful for measuring distances or angles between various features

    (tags: data-extraction scraping tools data charts)

  • 'Only aerosol transmission can explain' the Skagit Choir transmission incident

    Jose-Luis Jimenez on Twitter: The "Skagit Choir" incident of mass spreading of COVID-19 indicates aerosol transmission: 'Only aerosol transmission can explain how 1 person infected 52, including people who were 13 meters behind the index case.'

    (tags: aerosols covid-19 sars-cov-2 transmission infection air)

Links for 2020-09-30

  • inside the LAPD/LASD usage of Palantir

    Much of the LAPD data consists of the names of people arrested for, convicted of, or even suspected of committing crimes, but that’s just where it starts. Palantir also ingests the bycatch of daily law enforcement activity. Maybe a police officer was told a person knew a suspected gang member. Maybe an officer spoke to a person who lived near a crime “hot spot,” or was in the area when a crime happened. Maybe a police officer simply had a hunch. The context is immaterial. Once the LAPD adds a name to Palantir’s database, that person becomes a data point in a massive police surveillance system. [...] At great taxpayer expense, and without public oversight or regulation, Palantir helped the LAPD construct a vast database that indiscriminately lists the names, addresses, phone numbers, license plates, friendships, romances, jobs of Angelenos — the guilty, innocent, and those in between.
    This is absolute garbage -- total bias built-in. No evidence required to get a person in the firing line: “The focus of a data-driven surveillance system is to put a lot of innocent people in the system,” Ferguson said. “And that means that many folks who end up in the Palantir system are predominantly poor people of color, and who have already been identified by the gaze of police.”

    (tags: palantir databases privacy law lapd lasd los-angeles surveillance big-brother police crime gangs)

  • Everything you wanted to know about the Hydrogen economy but were too busy to research

    Informative Twitter thread: 'International hydrogen markets could be a thing, but don’t bet on hydrogen shipping'; 'H2 future looks good regardless'; and 'distributed plants could satisfy local industry and power markets while relieving electrical grid bottlenecks. The benefits are more likely to remain local rather than exported. So important for a just transition.' (via Forge The Future)

    (tags: h2 hydrogen green climate-change future eu europe twitter via:ftf)

  • AWS CRT HTTP Client in the AWS SDK for Java 2.x

    Interesting -- a new, high-performance, high-concurrency HTTP/1.1 client library in the AWS SDK, outperforming other Java HTTP client libs

    (tags: java libraries aws http http-1.1 clients)

Links for 2020-09-29

  • Covid: The libertarian population immunity strategy is wrong-headed & dangerous

    +1 to this --

    As cases of covid in the UK surge once again, the debate has restarted about whether to suppress covid until a vaccine becomes available, or whether to pursue a deliberate strategy of achieving population immunity without a vaccine. The assumption is that vulnerable populations can be protected while the rest of the population, who are at low risk of hospitalisation and death, can be safely encouraged to live life normally and be exposed to the virus without a vaccine. Some even advocate that younger people, because they are at lower risk, should be the first to actively seek infection. "Not only is it a good thing for young people to go out there and become immune," one commentator said, "but that is almost their duty". It is this deliberate strategy which I find so troubling, for six reasons. [....]

    (tags: uk politics covid-19 herd-immunity immunity risk pandemics)

Links for 2020-09-24

Links for 2020-09-23

  • Feh/nocache

    minimize filesystem caching effects:

    The nocache tool tries to minimize the effect an application has on the Linux file system cache. This is done by intercepting the open and close system calls and calling posix_fadvise() with the POSIX_FADV_DONTNEED parameter. Because the library remembers which pages (ie., 4K-blocks of the file) were already in file system cache when the file was opened, these will not be marked as "don't need", because other applications might need that, although they are not actively used (think: hot standby).

    (tags: cache linux memory performance filesystems backup k8s unix fadvise)

  • Now 11 reported SARS-CoV-2 reinfections

    4 cases were more serious the second time around

    (tags: reinfections sars-cov-2 covid-19)

Links for 2020-09-21

Links for 2020-09-17

Links for 2020-09-15

  • Rolling the COVID Dice in Ireland

    On the Probability of SARS-CoV2 Infection in Ireland & the Benefits of Mitigation: 'In Ireland today, we have a certain chance of becoming infected with the coronavirus over the course of the next week, unless we take precautions. We can roll this many sided dice once a week for 100 weeks, and hope that our number doesn’t ever come up, or we can take a few simple precautions and only roll the dice one time. That’s the difference wearing a mask, keeping our distance, and behaving sensibly makes. That’s the choice most of us can make to keep everyone safe. I think it’s a simple choice.'

    (tags: covid-19 barry-smyth probability safety infection)

Links for 2020-09-14

Links for 2020-09-11

  • Benchspace PPE Project Report

    report from Benchspace on their open source PPE project during March and April. it's great stuff. 50,000 face shields printed!

    (tags: face-shields covid-19 volunteers open-source 3d-printing ppe benchspace)

  • America Is Trapped in a Pandemic Spiral - The Atlantic

    'Many Americans trusted intuition to help guide them through this disaster. They grabbed onto whatever solution was most prominent in the moment, and bounced from one (often false) hope to the next. They saw the actions that individual people were taking, and blamed and shamed their neighbors. They lapsed into magical thinking, and believed that the world would return to normal within months. Following these impulses was simpler than navigating a web of solutions, staring down broken systems, and accepting that the pandemic would rage for at least a year. These conceptual errors were not egregious lies or conspiracy theories, but they were still dangerous. They manifested again and again, distorting the debate around whether to stay at home, wear masks, or open colleges. They prevented citizens from grasping the scope of the crisis and pushed leaders toward bad policies. And instead of overriding misleading intuitions with calm and considered communication, those leaders intensified them. The country is now trapped in an intuition nightmare: Like the spiraling ants, Americans are walled in by their own unhelpful instincts, which lead them round and round in self-destructive circles.'

    (tags: covid-19 america pandemics society failure ed-yong)

Links for 2020-09-09

Links for 2020-09-08

  • illustration of how a rise in SARS-CoV-2 positivity in younger groups can soon become a rise in older groups

    via Vincent Glad, on Twitter: the positivity rate stratified by age, in the Marseilles region

    (tags: testing covid-19 age epidemiology dataviz statistics marseilles france)

  • The timing of COVID-19 transmission

    new preprint on medRxiv:

    We examined the distribution of transmission events with respect to exposure and onset of symptoms. We show that for symptomatic individuals, the timing of transmission of SARS-CoV-2 is more strongly linked to the onset of clinical symptoms of COVID-19 than to the time since infection. We found that it was approximately centered and symmetric around the onset of symptoms, with three quarters of events occurring in the window from 2-3 days before to 2-3 days after. However, we caution against overinterpretation of the right tail of the distribution, due to its dependence on behavioural factors and interventions. We also found that the pre-symptomatic infectious period extended further back in time for individuals with longer incubation periods. This strongly suggests that information about when a case was infected should be collected where possible, in order to assess how far into the past their contacts should be traced. Overall, the fraction of transmission from strictly pre-symptomatic infections was high (41%; 95%CI 31-50%), which limits the efficacy of symptom-based interventions, and the large fraction of transmissions (35%; 95%CI 26-45%) that occur on the same day or the day after onset of symptoms underlines the critical importance of individuals distancing themselves from others as soon as they notice any symptoms, even if they are mild. Rapid or at-home testing and contextual risk information would greatly facilitate efficient early isolation.

    (tags: covid-19 transmission infection epidemiology)

  • AVIF has landed

    the latest hot new image format -- pretty impressive compression numbers vs quality thresholds here

    (tags: images web avif webp jpeg compression formats)

  • [MA] Post-it notes left in apartment. : legaladvice

    Classic Reddit thread. Guy finds mysterious post-it notes around his apartment, suspects his landlord is breaking in and leaving them. I won't spoil it, but it's quite a twist ending...

    (tags: reddit stories legaladvice apartments landlords post-its)

Links for 2020-09-07

Links for 2020-09-06

Links for 2020-09-05

  • Death, sex, superstition and fear: the hawthorn tree in Ireland

    These trees that grew of their own accord, unplanted by human hands, are those most regarded with fear and superstition. These are thought of as faery trees, associated with those unseen beings from the other world.  They are believed to mark the places where the faeries, after dark, would assemble and play sweet ethereal music, ready to abduct any beautiful human who took their fancy. Faeries could potentially destroy the crops, livestock, health, fortune or luck of anyone they took a dislike to, or anyone who had somehow wronged them. Thus, anything associated with faery activity in Ireland was traditionally avoided by the people who used many rituals to appease them.

    (tags: hawthorn trees superstition fairies sidhe history ireland folklore)

Links for 2020-09-04

Links for 2020-09-02

Links for 2020-08-26

Links for 2020-08-24

  • Interchange fee

    TIL about credit card "interchange fees" -- an additional fee levied by credit card companies and banks, roughly 3%, mainly in the US (the EU regulations cap it at 0.3%). 'Imagine a consumer making a $100 purchase with a credit card. For that $100 item, the retailer would get approximately $98. The remaining $2, known as the merchant discount[13] and fees, gets divided up.'

    (tags: fees credit-cards interchange-fees us money)

  • How I helped fix Canada?s COVID Alert app

    Nice writeup of using mitmproxy to detect unwanted accesses to a Google endpoint in an iOS app

    (tags: mitmproxy mitm https ios apps reversing)

  • interesting results on children and COVID-19 -- high asymptomatic infection rate

    'METHODS: We conducted a prospective cohort study of children and adolescents (<21 years of age) with a SARS-CoV-2-infected close contact. We collected nasopharyngeal or nasal swabs at enrollment and tested for SARS-CoV-2 using a real-time PCR assay. RESULTS: Of 382 children, 293 (77%) were SARS-CoV-2-infected. SARS-CoV-2-infected children were more likely to be Hispanic (p<0.0001), less likely to have asthma (p=0.005), and more likely to have an infected sibling contact (p=0.001) than uninfected children. Children ages 6-13 years were frequently asymptomatic (39%) and had respiratory symptoms less often than younger children (29% vs. 48%; p=0.01) or adolescents (29% vs. 60%; p<0.0001). Compared to children ages 6-13 years, adolescents more frequently reported influenza-like (61% vs. 39%; p<0.0001), gastrointestinal (27% vs. 9%; p=0.002), and sensory symptoms (42% vs. 9%; p<0.0001), and had more prolonged illnesses [median (IQR) duration: 7 (4, 12) vs. 4 (3, 8) days; p=0.01]. Despite the age-related variability in symptoms, we found no differences in nasopharyngeal viral load by age or between symptomatic and asymptomatic children.'

    (tags: covid-19 sars-cov-2 papers preprints kids children)

  • Children in close contact with a confirmed case of Covid-19 were not contacted for nine days

    'Children who came into close contact with a confirmed case of the coronavirus at a summer camp run by Ireland’s lead sporting authority were not contacted by the HSE regarding the issue for nine days, it has emerged. Sport Ireland, the State authority charged with the development of sport in Ireland, has been running childrens’ summer camps at the National Aquatic Centre campus in Blanchardstown, Dublin, where SI itself is headquartered, since June 29th. At one such camp on Friday, 14 August, a nine-year-old boy participating apparently came into close contact with a case of the virus. However, he heard nothing about the contact until nine days later on August 23 when his mother received an automated text message stating that the contact had occurred and that he had been referred for a Covid-19 test.'

    (tags: sport-ireland ireland contact-tracing covid-19 kids hse children)

Links for 2020-08-20

Links for 2020-08-17

Links for 2020-08-14

  • Air pollution is much worse than we thought. Climate change is far from the only problem with fossil fuels. - Vox

    “Over the next 50 years, keeping to the 2°C pathway would prevent roughly 4.5 million premature deaths, about 3.5 million hospitalizations and emergency room visits, and approximately 300 million lost workdays in the US.” All that prevented death, illness, and lost productivity adds up to a lot of savings: The avoided deaths are valued at more than $37 trillion. The avoided health care spending due to reduced hospitalizations and emergency room visits exceeds $37 billion, and the increased labor productivity is valued at more than $75 billion. On average, this amounts to over $700 billion per year in benefits to the US from improved health and labor alone, far more than the cost of the energy transition. Importantly, many of the benefits can be accessed in the near term. Right now, air pollution leads to almost 250,000 premature deaths a year in the US. Within a decade, aggressive decarbonization could reduce that toll by 40 percent; over 20 years, it could save around 1.4 million American lives that would otherwise be lost to air quality. Of the potential yearly deaths prevented, Rep. Robin Kelly of Illinois remarked at the hearing, “That’s a huge number. That’s nearly three times the number of lives we lose in car accidents every year. It’s twice the number of deaths caused by opioids in the past few years. And it’s even more than the number of Americans we lose to diabetes each year.”

    (tags: pollution air energy environment climate-change air-quality health decarbonization)

  • ESB PVC Ducting Pipe Red 50mm x 6M

    decent weatherproof ducting for running cables to garden sheds etc.

    (tags: ducting sheds garden home wiring cabling cables)

  • Excellent thread on the Ofqual justification for the UK's current approach to estimating A-level results

    Some prime quotes: 'You can’t infer the correct grades at an individual level from the prior year’s distribution of grades, no matter how hard you clonk away at the abacus.' 'The data *doesn’t* allow that. ThIs puts idea that grade inflation, school level results and maintaining the distribution shape is more important than the fairness of individual results.' 'I don’t blame Ofqual, but they’re being asked to correctly estimate the size of each egg that went into an omelette, based on a different omelette.'

    (tags: ofqual uk education covid-19 estimation a-levels grades schools)

  • Robust T cell immunity in convalescent individuals with asymptomatic or mild COVID-19: Cell

    Good news for ongoing immunity:

    SARS-CoV-2-specific memory T cells will likely prove critical for long-term immune protection against COVID-19. We here systematically mapped the functional and phenotypic landscape of SARS-CoV-2-specific T cell responses in unexposed individuals, exposed family members, and individuals with acute or convalescent COVID-19. Acute phase SARS-CoV-2-specific T cells displayed a highly activated cytotoxic phenotype that correlated with various clinical markers of disease severity, whereas convalescent phase SARS-CoV-2-specific T cells were polyfunctional and displayed a stem-like memory phenotype. Importantly, SARS-CoV-2-specific T cells were detectable in antibody-seronegative exposed family members and convalescent individuals with a history of asymptomatic and mild COVID-19. Our collective dataset shows that SARS-CoV-2 elicits robust, broad and highly functional memory T cell responses, suggesting that natural exposure or infection may prevent recurrent episodes of severe COVID-19.

    (tags: immunity covid-19 sars-cov-2 diseases immune-system t-cells)

Links for 2020-08-12

Links for 2020-08-11

Links for 2020-08-10

  • The effect of school closures and reopening strategies on COVID-19 infection dynamics in the San Francisco Bay Area: a cross-sectional survey and modeling analysis | medRxiv

    New preprint, modelling COVID-19 transmission in Bay Area schools.

    Large-scale school closures have been implemented worldwide to curb the spread of COVID-19. However, the impact of school closures and re-opening on epidemic dynamics remains unclear. Methods: We simulated COVID-19 transmission dynamics using an individual-based stochastic model, incorporating social-contact data of school-aged children during shelter-in-place orders derived from Bay Area (California) household surveys. We simulated transmission under observed conditions and counterfactual intervention scenarios between March 17-June 1, and evaluated various fall 2020 K-12 reopening strategies. Findings: Between March 17-June 1, assuming children <10 were half as susceptible to infection as older children and adults, we estimated school closures averted a similar number of infections (13,842 cases; 95% CI: 6,290, 23,040) as workplace closures (15,813; 95% CI: 9,963, 22,617) and social distancing measures (7,030; 95% CI: 3,118, 11,676). School closure effects were driven by high school and middle school closures. Under assumptions of moderate community transmission, we estimate that fall 2020 school reopenings will increase symptomatic illness among high school teachers (an additional 40.7% expected to experience symptomatic infection, 95% CI: 1.9, 61.1), middle school teachers (37.2%, 95% CI: 4.6, 58.1), and elementary school teachers (4.1%, 95% CI: -1.7, 12.0). Results are highly dependent on uncertain parameters, notably the relative susceptibility and infectiousness of children, and extent of community transmission amid re-opening. The school-based interventions needed to reduce the risk to fewer than an additional 1% of teachers infected varies by grade level. A hybrid-learning approach with halved class sizes of 10 students may be needed in high schools, while maintaining small cohorts of 20 students may be needed for elementary schools. Interpretation: Multiple in-school intervention strategies and community transmission reductions, beyond the extent achieved to date, will be necessary to avoid undue excess risk associated with school reopening. Policymakers must urgently enact policies that curb community transmission and implement within-school control measures to simultaneously address the tandem health crises posed by COVID-19 and adverse child health and development consequences of long-term school closures.

    (tags: covid-19 bay-area schools kids transmission models)

Links for 2020-08-04

  • Nisreen A Alwan: What exactly is mild covid-19? 

    What is now becoming clear is that mortality is not the only adverse outcome of this infection and our surveillance systems must keep up and reflect that. I am advocating for precise case definitions for covid-19 morbidity that reflect the degree of severity of infection and allow us to measure moderate and long term health and wellbeing outcomes. At this stage of the pandemic, it is vital that we accurately measure and count all degrees of infection, not only in research cohorts, but as part of population-based routine surveillance systems. This includes people like me who were not tested at the time of their initial infection. Death is not the only thing to count in this pandemic, we must count lives changed. We still know very little about covid-19, but we do know that we cannot fight what we do not measure. 

    (tags: covid-19 diseases fatigue symptoms medicine bmj)

  • Georgia camp outbreak shows rapid virus spread among children

    Between 44% and 75% of the people at this summer camp were infected. '258 staff gathered for three days before the camp started with no precautions. Then on day 1 of camp someone [felt] chills. By day 6, the camp was closed.' 597 attendees, 344 tested, 260 positive.

    (tags: covid-19 symptoms summer-camps pandemic disease georgia kids schools children)

  • "Three new important studies came out in the past week about kids & COVID-19"

    Good twitter thread from Megan Ranney MD: * 'South Korea study -- Older kids most likely transmit #COVID19 to their household at rates similar to adults. And younger kids transmit the virus, too. But: no masks or distancing, since this took place at home.' * 'Chicago -- the level of the virus in kids is AT LEAST as high as the level of virus in adults. (Caveat: we don't know whether this virus is infectious. But this data matches what we know about other respiratory viruses. The next step will be studying test swabs to see if kids' virus can reproduce. I suspect it can. [...] We can't let kids ignore #SocialDistancing & #MaskUp just bc they're kids.)' * 'States with early closure of schools had reduced levels of #COVID19 compared with states with late closure, *even after* adjusting for policies like "stay-at-home". [...] Once #COVID19 infection rates start to rise, it would be foolhardy to keep schools open IRL. And we should be planning NOW for how to keep kids healthy, safe, & fed, because that moment will likely come for every state.' 'Realistically, we MUST control levels of community transmission of #COVID19 if we want kids & teachers in schools. We may be able to send kids back, but we need PPE & regular, random testing of kids & teachers, whether in elementary, middle, high school, or college.'

    (tags: parenting kids schools covid-19 transmission pandemics viruses sars-cov-2)

  • The UX of LEGO Interface Panels – George Cave

    love it

    (tags: lego ux ui design funny)

  • RCP8.5 tracks cumulative CO2 emissions | PNAS

    Today in "we are still fucked" news:

    RCP8.5, the most aggressive scenario in assumed fossil fuel use for global climate models, will continue to serve as a useful tool for quantifying physical climate risk, especially over near- to midterm policy-relevant time horizons. Not only are the emissions consistent with RCP8.5 in close agreement with historical total cumulative CO2 emissions (within 1%), but RCP8.5 is also the best match out to midcentury under current and stated policies with still highly plausible levels of CO2 emissions in 2100.
    RCP8.5 is the model associated with a planet where a good chunk of the globe is rendered uninhabitable.

    (tags: rcp8.5 grim-meathook-future future climate-change co2 pnas papers models climate)

  • Evidence for sustained mucosal and systemic antibody responses to SARS-CoV-2 antigens in COVID-19 patients | medRxiv

    While the antibody response to SARS-CoV-2 has been extensively studied in blood, relatively little is known about the mucosal immune response and its relationship to systemic antibody levels. Since SARS-CoV-2 initially replicates in the upper airway, the antibody response in the oral cavity is likely an important parameter that influences the course of infection. We developed enzyme linked immunosorbent assays to detect IgA and IgG antibodies to the SARS-CoV-2 spike protein (full length trimer) and its receptor binding domain (RBD) in serum (n=496) and saliva (n=90) of acute and convalescent patients with laboratory-diagnosed COVID-19 ranging from 3-115 days post-symptom onset (PSO), compared to negative controls. Anti-CoV-2 antibody responses were readily detected in serum and saliva, with peak IgG levels attained by 16-30 days PSO. Whereas anti-CoV-2 IgA antibodies rapidly decayed, IgG antibodies remained relatively stable up to 115 days PSO in both biofluids. Importantly, IgG responses in saliva and serum were correlated, suggesting that antibodies in the saliva may serve as a surrogate measure of systemic immunity.
    That last line, in particular, is good news.

    (tags: covid-19 immunity disease assays antibodies sars-cov-2 papers preprints)

  • Harvard-UC Boulder Portable Air Cleaner Calculator for Schools

    A handy calculator spreadsheet to estimate how big of a portable air cleaner would be required to protect kids/teachers/admin staff at a typical US school, based on room size, ceiling height, etc. More info: https://twitter.com/cedenolaurent/status/1290447833959747584 (Catherine Lalanne notes: "Airflows in this sheet are about half the Irish regulations, American regulations are pretty weak.")

    (tags: air-cleaners filtration spreadsheets covid-19 schools kids air-quality air)

Links for 2020-07-31

Links for 2020-07-30

Links for 2020-07-29

  • US Spring school closures tied to drastic decrease in Covid-19 cases, deaths in model

    Their projection found that, if schools had stayed open, there could have been roughly 424 more coronavirus infections and 13 more deaths per 100,000 residents over the course of 26 days. Extrapolate that to the American population, and the country might have seen as many as 1.37 million more cases and 40,600 more deaths, explained Samir Shah, the director of hospital medicine at Cincinnati Children’s Hospital Medical Center and one of the authors of the paper. “These numbers seem ridiculously high and it’s mind-boggling to think that these numbers are only … in the first several weeks,” said Shah. “That’s bonkers.” He warned, though, that those numbers should be taken with a grain of salt. While their statistical model attempts to pinpoint the impact of schools staying open or being closed, the method can’t actually establish any sort of causal relationship.

    (tags: models modelling schools reopening covid-19 kids us)

Links for 2020-07-28

  • School openings across globe suggest ways to keep coronavirus at bay, despite outbreaks | Science | AAAS

    When Science looked at reopening strategies from South Africa to Finland to Israel, some encouraging patterns emerged. Together, they suggest a combination of keeping student groups small and requiring masks and some social distancing helps keep schools and communities safe, and that younger children rarely spread the virus to one another or bring it home. But opening safely, experts agree, isn’t just about the adjustments a school makes. It’s also about how much virus is circulating in the community, which affects the likelihood that students and staff will bring COVID-19 into their classrooms.

    (tags: covid-19 education schools pods children kids)

Links for 2020-07-27

  • AWS User Data is Being Stored, Used Outside User's Chosen Regions

    Wow, this is staggeringly inappropriate usage. Bad move, Amazon!

    [AWS] is using customers’ “AI content” for its own product development purposes. It also reserves the right in its small print to store this material outside the geographic regions that AWS customers have explicitly selected. It may also share this with AWS “affiliates” it says, without naming them.

    (tags: via:corey-quinn aws amazon machine-learning corpora training data data-privacy data-protection)

  • The Scourge of Hygiene Theater - The Atlantic

    On the pointless "deep clean":

    To some American companies and Florida men, COVID-19 is apparently a war that will be won through antimicrobial blasting, to ensure that pathogens are banished from every square inch of America’s surface area. But what if this is all just a huge waste of time? In May, the Centers for Disease Control and Prevention updated its guidelines to clarify that while COVID-19 spreads easily among speakers and sneezers in close encounters, touching a surface “isn’t thought to be the main way the virus spreads.” Other scientists have reached a more forceful conclusion. “Surface transmission of COVID-19 is not justified at all by the science,” Emanuel Goldman, a microbiology professor at Rutgers New Jersey Medical School, told me. He also emphasized the primacy of airborne person-to-person transmission.

    (tags: covid-19 air aerosols transmission cleaning surfaces fomites hygiene)

Links for 2020-07-26

  • Sputum testing provides higher rate of COVID-19 detection | EurekAlert! Science News

    Li and his colleagues scoured the literature -- both preprints and published papers -- for studies that assessed at least two respiratory sampling sites using an NP swab, oropharyngeal swab or sputum. From more than 1,000 studies, they identified 11 that met their criteria. These studies included results from a total of 3,442 respiratory tract specimens. The team examined how often each collection method produced a positive result. For NP swabs, the rate was 54 percent; for oropharyngeal swabs, 43 percent; for sputum, 71 percent. The rate of viral detection was significantly higher in sputum than either oropharyngeal swabs or NP swabs. Detection rates were highest within one week of symptom onset for all three tests.

    (tags: sputum covid-19 testing swabs)

Links for 2020-07-25

  • COVID Dogs

    Scent dog identification of samples from COVID-19 patients – a pilot study, in BMC Infectious Diseases:

    The dogs were able to discriminate between samples of infected (positive) and non-infected (negative) individuals with average diagnostic sensitivity of 82.63% (95% confidence interval [CI]: 82.02–83.24%) and specificity of 96.35% (95% CI: 96.31–96.39%). During the presentation of 1012 randomised samples, the dogs achieved an overall average detection rate of 94% (±3.4%) with 157 correct indications of positive, 792 correct rejections of negative, 33 incorrect indications of negative or incorrect rejections of 30 positive sample presentations.

    (tags: dogs good-dog covid-19 detection testing smell scent)

Links for 2020-07-23

  • Top Scientists Just Ruled Out Best-Case Global Warming Scenarios - Bloomberg

    "A group of 25 leading scientists now conclude that catastrophic warming is almost inevitable if emissions continue at their current rate."

    (tags: global-warming climate-change future climate science)

  • 20 Questions to Ask before Sending your Kids Back to School – Schools For Health

    An excellent checklist.

    There is no such thing as “zero risk” in anything we do, and certainly not during a pandemic. There will be some risk to students, teachers, staff, and families. As such, it is important to reduce these risks to the extent possible. Returning to school should not be “school as usual.” We prepared the following set of questions as a guide for parents, teachers and school staff who may not be sure what to ask or look for at their school. While we offer some insight into the responses you might receive, and expect, each school’s response will be different because there is no “one size fits all” plan for COVID-19.

    (tags: schools teaching covid-19 health kids children)

  • Schools Will Eventually Need to Reopen – Schools For Health

    We recognize there are immense challenges. There is no perfect plan to reopen schools safely, only “less bad” options. There is no “one size fits all” strategy that works for every school. Schools have limited budgets and staff. Compliance will be imperfect. Learning will be different. There will be disruption. Schools may need to re-close unexpectedly depending on local conditions. No one knows with certainty what the fall will bring in terms of this pandemic. Despite these challenges, the enormous individual and societal costs of keeping schools closed compels us, a team focused on Healthy Buildings and exposure and risk science, to present a range of control strategies that should be considered in discussions of school reopenings.

    (tags: health schools reopening covid-19 teaching kids children)

  • Facebook Employee Leaks Show Betrayal By Company Leadership

    Wang opted for a clip of himself speaking directly to the camera. What followed was a 24-minute clear-eyed hammering of Facebook’s leadership and decision-making over the previous year. The video was a distillation of months of internal strife, protest, and departures that followed the company’s decision to leave untouched a post from President Donald Trump that seemingly called for violence against people protesting the police killing of George Floyd. And while Wang’s message wasn’t necessarily unique, his assessment of the company’s ongoing failure to protect its users — an evaluation informed by his lengthy tenure at the company — provided one of the most stunningly pointed rebukes of Facebook to date. “We are failing,” he said, criticizing Facebook’s leaders for catering to political concerns at the expense of real-world harm. “And what's worse, we have enshrined that failure in our policies.”

    (tags: activism ethics facebook work policies nazis trump)

Links for 2020-07-21

Links for 2020-07-20

  • Cancel Culture and the Problem of Woke Capitalism - The Atlantic

    'How Capitalism Drives Cancel Culture: Beware splashy corporate gestures when they leave existing power structures intact.'

    (tags: cancel-culture cancelling capitalism society)

  • The inside story of how the UK government failed to develop a contact-tracing app

    A classic Tory fuckup. Spoofing, over-promising, a behind-the-scenes desire to collect a database of citizen's private medical info, and hubris.

    (tags: nhsx palantir bluetooth covid-19 uk tories data-privacy nhs)

  • Ireland donates its contact tracing app to the Linux Foundation

    This is awesome. Congrats to NearForm and the HSE for making some great choices here:

    Ireland’s Health Service Executive (HSE) announced today that it is donating the code for the COVID Tracker app as Open Source to the not-for-profit Linux Foundation. This will enable jurisdictions worldwide to quickly build and deploy their own contact tracing apps using a wildly successful proven base. The donated app has been named COVID Green. [...] The rapid adoption of the COVID Tracker app in Ireland exceeded all expectations. One million people installed it in the first 36 hours, and the app currently has over 1.3 million installations. That figure represents more than 30% of people in Ireland with compatible devices. The code is also being used in the app for Gibraltar and the upcoming apps for Northern Ireland, other jurisdictions in EMEA and multiple US states. NearForm continues to enable public health authorities to get a contact tracing application into production within four weeks of project start. By donating the source code to the new Linux Foundation Public Health (LFPH) project, under the Apache License 2.0, the HSE is playing an active role in helping to fight Covid-19 worldwide. Source code for the COVID Green mobile app is available now on GitHub and soon will be followed by all matching backend code. The Linux Foundation is dedicated to building sustainable ecosystems around open source projects to accelerate technology development and industry adoption. LFPH is launching with a mission to use open source software to help public health authorities (PHAs) around the world combat Covid-19 and future epidemics. One of the roles of LFPH is to serve as a forum for collaboration between PHAs, developers, technology companies and academics to ensure the implementation and dissemination of best practices, including privacy and security.

    (tags: hse nearform covid-19 contact-tracing exposure-notification apps mobile open-source linux-foundation lfph)

Links for 2020-07-17

  • Turkey Now Has Swarming Suicide Drones It Could Export - The Drive

    Well, this is pretty scary -- swarming autonomous kamikaze drones are actively in production right now:

    It seems very possible that, in addition to providing these improved Kargu [drones] to the Turkish armed forces, STM could also seek to export them, proliferating this capability further around the world. STM has already said that it has received serious inquires about the Kargu series from at least three unnamed potential foreign customers. Turkey, as a whole, has become a powerhouse of drone development and production, employing larger types to great effect in Syria and Libya just this year. This is precisely the type of weapon we have been warning about for years now. The fact that it is already here and potentially exportable should be yet another wake-up call to the level of threat low-end drones pose to U.S. and allied forces, as well as domestic infrastructure and VIPs.  "I argue all the time with my Air Force friends that the future of flight is vertical and it's unmanned," U.S. Marine General Kenneth McKenzie, head of U.S. Central Command, said at an event hosted by the Middle East Institute last week. "I'm not talking about large unmanned platforms, which are the size of a conventional fighter jet that we can see and deal with, as we would any other platform." "I'm talking about the one you can go out and buy at Costco right now in the United States for a thousand dollars, four quad, rotorcraft or something like that that can be launched and flown," he continued. "And with very simple modifications, it can make made into something that can drop a weapon like a hand grenade or something else."

    (tags: drones war terrorism ai autonomous scary kargu kerkes turkey stm)

  • interesting data on COVID-19 rates among school-age kids

    Twitter thread:

    Highest COVID-19 rate (18.6%) for household contacts of school-aged children and lowest (5.3%) for household contacts of kids 0-9; - School closure and distancing reduced rate of COVID-19 among contacts of school aged kids. What does this mean? - I believe this further supports that we need to have low rates of community transmission before we consider opening up schools; - Per this data kids 10-19 had highest rates of contacts with COVID-19; - This is scientific data, let this lead our decision.

    (tags: contact-tracing south-korea schools reopening covid-19 transmission children)